(Italiano) Istituto di Cristallografia - CNR

(Italiano) Sito web ufficiale dell'Istituto di Cristallografia del Consiglio Nazionale delle ricerche

BIOTECH – IC MONTELIBRETTI

by · May 15, 2020

 

 DESCRIPTION: 

The group BIOTECH is a multidisciplinary research team working synergistically to identify and characterize biological systems suitable for technological transfer in the agri-food, biomedical and environmental sectors. Through a multi-tiered approach, products and processes with high biotechnological potential have been achieved in the following thematic areas:

i) NANOBIONICS, aiming at increasing biomass and bio-hydrogen production in green algae through the exploitation of nanostructured polymeric systems with photonic and electronic properties

ii) (BIO)SENSORS, aiming at developing robust and selective (bio)sensing elements and novel multi-transduction (bio)sensors for environmental and agri-food monitoring

iii) BIOPROSPECTING, aiming at unravelling and evaluating the bio-prospection potential of stress-induced molecules involved in the adaptive responses of Antarctic terrestrial meiofauna (Tardigrades) in response to harmful UV radiation and temperature.

iv) BIO-NANOMEDICINE, aiming at developing nanoparticles-based countermeasures for treatment of microgravity induced osteoporosis by an in vitro study of the bone remodeling process; and at deeper the knowledge on DNA repair processes and mitochondrial stability in the Cockayne’s syndrome

Contact Person:
GIUSEPPINA REA
Tel: 06 90672631: e-mail: giuseppina.reaATmlib.ic.cnr.it

 
 
 INVOLVED STAFF: 

KATIA BUONASERA
Tel: 06 90672447; e-mail: katia.buonaseraATmlib.ic.cnr.it

LOREDANA CACCAVALE
Tel: 06 90672634; e-mail: loredana.caccavaleATmlib.ic.cnr.it

GAETANO CAMPI
Tel: 06 90672624; e-mail: gaetano.campiATmlib.ic.cnr.it

GABRIELE FAVARETTO
Tel: 06 90672634; e-mail: gabriele.favarettoATmlib.ic.cnr.it

MAYA DIMOVA LAMBREVA
Tel: 0690672921; e-mail: maya.lambrevaATmlib.ic.cnr.it

TERESA LAVECCHIA
Tel: 0690672479; e-mail: teresalv1977ATgmail.com

ANDREA MARGONELLI
Tel: e-mail: andrea.margonelliATmlib.ic.cnr.it

BARBARA PASCUCCI
Tel: 06 90672631; 06 49902560; e-mail: barbara.pascucciATmlib.ic.cnr.it

ROBERTO PILLOTON
Tel: 3313291173; e-mail: roberto.pillotonATcnr.it

 
 
 FACILITES AND LABORATORIES: 

 
 
 GROUP RELATED RESEARCH PROJECTS: 

2015-2017. Progetto Bilaterale con la Russia (CNR/RFBR): Impiego della nanobionica per ottimizzare la fotosintesi e la produttività algale. Responsabile IC: Maya D. Lambreva.

2016-2018. PRIN 2015. Ubiquitin E3 ligases as critical sensors in physiological and pathological conditions. MIUR Prot. 20152CB22L. Responsabile IC: Barbara Pascucci.

2014-2016. CONTRATTO ASI N. 2013-060-I.0 Bando di Volo Umano Spaziale per ricerche e dimostrazioni tecnologiche sulla ISS DC-MIC-2012-024. Agenzia Spaziale Italiana (ASI). Titolo: NAnoparticles based countermeasures for Treatment of microgravity induced Osteoporosis (NATO). Responsabile IC: Giuseppina Rea.

2014-2016. Bando PRNA 11.3.2013, n. 417. Ministero dell’Istruzione, dell’Università e della Ricerca. Titolo: Physiological, biochemical and transcriptomic adaptive responses to harmful UV radiation and temperature increases in Antarctic meiofaunal organisms: a walk from genes to organisms. Responsabile IC: Giuseppina Rea.

2016-2018 Progetto bilaterale con l’India (CNR-CSIR): A Rapid High Performance Biosensor based on Gold Nanoparticle Anchored Graphene Sheets for the Electrochemical Detection of Biomarkers and DNA mutations for clinical and environmental applications. Responsabile IC Roberto Pilloton.

 
 
 GROUP RELATED PUBLICATIONS : 

Pascucci B, D’Errico M, Romagnoli A, De Nuccio C, Savino M, Pietraforte D, Lanzafame M, Calcagnile AS, Fortini P, Baccarini S, Orioli D, Degan P, Visentin S, Stefanini M, Isidoro C, Fimia GM, Dogliotti E. (2017). Overexpression of parkin rescues the defective mitochondrial phenotype and the increased apoptosis of Cockayne Syndrome A cells. Oncotarget 8:102852-102867.
Campi G., Cristofaro F., Pani G., Fratini M., Pascucci B., Corsetto P.A., Weinhauseng B., Cedola A., Rizzo A.M., Visai L. and Rea G. (2017). Heterogeneous and self-organizing mineralization of bone matrix promoted by hydroxyapatite nanoparticles. Nanoscale 9(44), 17274-17283.
I. Husu, G. Rodio, E. Touloupakis, M.D. Lambreva, K. Buonasera, S.C. Litescu, M.T. Giardi, G. Rea (2013). Insights into photo-electrochemical sensing of herbicides driven by Chlamydomonas reinhardtii cells. Sensors & Actuators: B. Chemical 185: 321–330.
Lambreva, M.D., Lavecchia, T., Tyystjärvi, E., Antal, T.K., Orlanducci, S., Margonelli, A., Rea, G. (2015). Potential of carbon nanotubes in algal biotechnology. Photosynthesis research, 1-21.
Lambreva MD, Giardi MT, Rambaldi I, Antonacci A, Pastorelli S, Bertalan I., Husu I., Johanningmeier U, Rea G. (2013) A Powerful Molecular Engineering Tool Provided Efficient Chlamydomonas Mutants as Bio-Sensing Elements for Herbicides Detection. PLoS ONE 8(4): e61851.
Malvano F, Albanese D, Pilloton R, Di Matteo M,Crescitelli A, (2017) A New Label-Free Impedimetric Affinity Sensor Based on Cholinesterases for Detection of Organophosphorous and Carbamic Pesticides in Food Samples: Impedimetric Versus Amperometric Detection; Food Bioprocess Technol; DOI 10.1007/s11947-017-1955-7.