The group BIOTECH is a multidisciplinary research team working synergistically to identify and characterize biological systems suitable for technological transfer in the agri-food, biomedical and environmental sectors. Through a multi-tiered approach, products and processes with high biotechnological potential have been achieved in the following thematic areas:
i) NANOBIONICS, aiming at increasing biomass and bio-hydrogen production in green algae through the exploitation of nanostructured polymeric systems with photonic and electronic properties
ii) (BIO)SENSORS, aiming at developing robust and selective (bio)sensing elements and novel multi-transduction (bio)sensors for environmental and agri-food monitoring
iii) BIOPROSPECTING, aiming at unravelling and evaluating the bio-prospection potential of stress-induced molecules involved in the adaptive responses of Antarctic terrestrial meiofauna (Tardigrades) in response to harmful UV radiation and temperature.
iv) BIO-NANOMEDICINE, aiming at developing nanoparticles-based countermeasures for treatment of microgravity induced osteoporosis by an in vitro study of the bone remodeling process; and at deeper the knowledge on DNA repair processes and mitochondrial stability in the Cockayne’s syndrome
Tel: 06 90672631: e-mail: giuseppina.reaATmlib.ic.cnr.it
FACILITES AND LABORATORIES:
GROUP RELATED RESEARCH PROJECTS:
GROUP RELATED PUBLICATIONS :
Pascucci B, D’Errico M, Romagnoli A, De Nuccio C, Savino M, Pietraforte D, Lanzafame M, Calcagnile AS, Fortini P, Baccarini S, Orioli D, Degan P, Visentin S, Stefanini M, Isidoro C, Fimia GM, Dogliotti E. (2017). Overexpression of parkin rescues the defective mitochondrial phenotype and the increased apoptosis of Cockayne Syndrome A cells. Oncotarget 8:102852-102867.
Campi G., Cristofaro F., Pani G., Fratini M., Pascucci B., Corsetto P.A., Weinhauseng B., Cedola A., Rizzo A.M., Visai L. and Rea G. (2017). Heterogeneous and self-organizing mineralization of bone matrix promoted by hydroxyapatite nanoparticles. Nanoscale 9(44), 17274-17283.
I. Husu, G. Rodio, E. Touloupakis, M.D. Lambreva, K. Buonasera, S.C. Litescu, M.T. Giardi, G. Rea (2013). Insights into photo-electrochemical sensing of herbicides driven by Chlamydomonas reinhardtii cells. Sensors & Actuators: B. Chemical 185: 321–330.
Lambreva, M.D., Lavecchia, T., Tyystjärvi, E., Antal, T.K., Orlanducci, S., Margonelli, A., Rea, G. (2015). Potential of carbon nanotubes in algal biotechnology. Photosynthesis research, 1-21.
Lambreva MD, Giardi MT, Rambaldi I, Antonacci A, Pastorelli S, Bertalan I., Husu I., Johanningmeier U, Rea G. (2013) A Powerful Molecular Engineering Tool Provided Efficient Chlamydomonas Mutants as Bio-Sensing Elements for Herbicides Detection. PLoS ONE 8(4): e61851.
Malvano F, Albanese D, Pilloton R, Di Matteo M,Crescitelli A, (2017) A New Label-Free Impedimetric Affinity Sensor Based on Cholinesterases for Detection of Organophosphorous and Carbamic Pesticides in Food Samples: Impedimetric Versus Amperometric Detection; Food Bioprocess Technol; DOI 10.1007/s11947-017-1955-7.