Viviana Scognamiglio Pagina Personale
Viviana Scognamiglio
Viviana Scognamiglio, PhD
Istituto di Cristallografia
National Research Council – CNR
00015 Monterotondo Scalo, Rome, Italy
e-mail: viviana.scognamiglioATmlib.ic.cnr.it
Tel : +39 06 90672479
fax: +39 06 90672630
https://www.researchgate.net/profile/Viviana_Scognamiglio/
Qualifica Attuale : Ricercatore
Curriculum Vitae :
2002 : Degree in Molecular Biology at the Faculty of Science MM.FF.NN. at the University “Federico II” of Naples
2003 – 2004 : grants from BioTekNet within the project “Esperti in Applicazioni Industriali delle Biotecnologie”, at Institute of Protein Biochemistry, CNR of Naples
2004 – 2008 : grants within a PhD project in Industrial Biotechnology for the development of optical biosensors for the detection of glucose for diabetic patients for biomedical application, at Institute of Protein Biochemistry, CNR of Naples
2008 : PhD in Industrial Biotechnology at University “Federico II” of Naples
2008 : fellowship within MULTITASK project for the development of optical biosensors for agrofood application, at Institute of Crystallography, CNR of Rome
2008 – 2010 : researcher contract within FILAS grants “art. 41 comma 1 LR 9 del 17/02/2005” for the realisation of a biosensor/bioreactor for nutraceutic application (BIO-NUTRA project) at Institute of Crystallography, CNR of Rome
2010 – 2011 : researcher contract within SENSBIOSYN project grants for the realisation of electro-optical biosensors for nutraceutic application, at Institute of Crystallography, CNR of Rome
2011 on going : permanent position as researcher at Institute of Crystallography, CNR of Rome
Attività di Ricerca :
- selection and characterisation of microorganisms and enzymes/proteins by Fluorescence Spectroscopy and Circular Dichroism for the design of bioreceptors in the development of biosensor systems
- development of electrochemical-optical biosensors for the detection of analytes with environmental, agrifood and biomedical interest
- screening, characterisation and immobilisation of bioreceptors, fluorescence labelling, nanomaterial modification of biosebsing support, biosensor prototype validation, tests on real samples.
In particular, the researcher realised:
– optical biosensing systems for the detection of glucose for diabetic patients, to be applied in diagnostic and biomedical field, based on fluorescence spectroscopy technique;
– optical biosensing systems for the detection of gluten for celiac patients, to be applied in diagnostic and biomedical field, based on FRET (Fluorescence/Forster Resonance Energy Transfer) technique;
– electrochemical biosensors for the detection of pollutants in water and food to be applied in environmental and agrifood fields, based on amperometric technique and screen-printed electrodes (SPEs);
– combined electrochemical-optical biosensors for the follow-up of food quality and safety, for the detection of food components and contaminants to be applied in agrifood sector and to evaluate suitability of bioremediation processes, based on gold microelectrodes arrays (MEAs);
– optical bioassays and biosensors for the detection of chemical warfare agents and their simulants, to be applied in security field;
– amperometric and optical biosensing systems for the detection of antioxidant substances for nutraceutic application.
Pubblicazioni Scelte :
Antonacci, A., Bertalan, I., Giardi, M. T., Scognamiglio, V., Turemis, M., Fisher, D., & Johanningmeier, U. (2021). Enhancing resistance of Chlamydomonas reinhardtii to oxidative stress fusing constructs of heterologous antioxidant peptides into D1 protein. Algal Research, 54, 102184.
Giardi, M. T., Zappi, D., Turemis, M., Varani, G., Celso, F. L., Barone, G., … & Scognamiglio, V. (2021). Quantum dots functionalised artificial peptides bioinspired to the D1 protein from the Photosystem II of Chlamydomonas reinhardtii for endocrine disruptor optosensing. Talanta, 224, 121854.
Antonacci, A., Celso, F. L., Barone, G., Calandra, P., Grunenberg, J., Moccia, M., Scognamiglio*, V. (2020). Novel atrazine-binding biomimetics inspired to the D1 protein from the photosystem II of Chlamydomonas reinhardtii. International Journal of Biological Macromolecules, 163, 817-823.
Moccia, M., Antonacci, A., Saviano, M., Caratelli, V., Arduini, F., & Scognamiglio*, V. (2020). Emerging technologies in the design of Peptide Nucleic Acids (PNAs) based Biosensors. TrAC Trends in Analytical Chemistry, 116062.
Kumar, V., Sinha, A. K., Uka, A., Antonacci, A., Scognamiglio, V., Mazzaracchio, V., Arduini, F. (2020). Multi-potential biomarkers for seafood quality assessment: global wide implication for human health monitoring. TrAC Trends in Analytical Chemistry, 116056.
Attaallah, R., Antonacci, A., Mazzaracchio, V., Moscone, D., Palleschi, G., Arduini, F., & Scognamiglio*, V. (2020). Carbon black nanoparticles to sense algae oxygen evolution for herbicides detection: Atrazine as a case study. Biosensors and Bioelectronics, 112203.
Castrovilli, M. C., Bolognesi, P., Chiarinelli, J., Avaldi, L., Cartoni, A., Calandra, P., & Scognamiglio*, V. (2020). Electrospray deposition as a smart technique for laccase immobilisation on carbon black-nanomodified screen-printed electrodes. Biosensors and Bioelectronics, 112299.
Antonacci*, A., & Scognamiglio*, V. (2020). Biotechnological advances in the design of algae-based biosensors. Trends in Biotechnology, 38(3), 334-347.
Bartolucci, C., Antonacci, A., Arduini, F., Moscone, D., Fraceto, L., Campos, E., & Santander, J. M. P. (2020). Green nanomaterials fostering agrifood sustainability. TrAC Trends in Analytical Chemistry, 125, 115840.
Arduini, F., Micheli, L., Scognamiglio, V., Mazzaracchio, V., & Moscone, D. (2020). Sustainable materials for the design of forefront printed (bio) sensors applied in agrifood sector. TrAC Trends in Analytical Chemistry, 115909.
Arduini, F., Cinti, S., Mazzaracchio, V., Scognamiglio, V., Amine, A., & Moscone, D. (2020). Carbon black as an outstanding and affordable nanomaterial for electrochemical (bio) sensor design. Biosensors and Bioelectronics, 156, 112033.
Antonacci, A., Scognamiglio, V., Mazzaracchio, V., Caratelli, V., Fiore, L., Moscone, D., & Arduini, F. (2020). Paper Based Electrochemical Devices for the Pharmaceutical Field: State of the Art and Perspectives. Frontiers in Bioengineering and Biotechnology, 8.
Attaallah, R., Antonacci, A., Arduini, F., Amine, A., & Scognamiglio*, V. (2020). Nanobiosensors for Bioclinical Applications: Pros and Cons. In Green Nanoparticles (pp. 117-149). Springer, Cham.
Cacciotti, I., Pallotto, F., Scognamiglio, V., Moscone, D., & Arduini, F. (2020). Reusable optical multi-plate sensing system for pesticide detection by using electrospun membranes as smart support for acetylcholinesterase immobilisation. Materials Science and Engineering: C, 111, 110744.
Zappi, D., Ramma, M. M., Scognamiglio, V., Antonacci, A., Varani, G., & Giardi, M. T. (2020). High-Tech and Nature-Made Nanocomposites and Their Applications in the Field of Sensors and Biosensors for Gas Detection. Biosensors, 10(11), 176.
Attaallah, R., Antonacci, A., Arduini, F., Amine, A., Scognamiglio* V. (2019) Nanobiosensors for bioclinical applications: pros and cons, in Green Nanoparticles – Synthesis and Biomedical Applications, Eds. Jayanta Kumar Patra, Gitishree Das, Leonardo F. Fraceto, Estefânia Vangelie Ramos Campos, published by Springer Nature Switzerland (in press).
Arduini, F., Cinti, S., Scognamiglio, V., Moscone, D. (2019) Nanomaterial based-sensors, in Handbook of Nanomaterials in Analytical Chemistry, Ed. Chaudhery Mustansar Hussain, published by Elsevier, pp.329-355.
Scognamiglio* V., Arduini F. (2019). The technology tree in the design of glucose biosensors. TrAC Trends in Analytical Chemistry, 115642.
Castrovilli, M. C., Bolognesi, P., Chiarinelli, J., Avaldi, L., Calandra, P., Antonacci, A., Scognamiglio*, V. (2019). The convergence of forefront technologies in the design of laccase-based biosensors-an update. TrAC Trends in Analytical Chemistry.
Pagliarini, V., Neagu, D., Scognamiglio, V., Pascale, S., Scordo, G., Volpe, G., & Moscone, D. (2019). Treated Gold Screen-Printed Electrode as Disposable Platform for Label-Free Immunosensing of Salmonella Typhimurium. Electrocatalysis, 10(4), 288-294.
Antonacci, A., & Scognamiglio, V. (2019). Photosynthesis-based hybrid nanostructures: electrochemical sensors and photovoltaic cells as case studies. TrAC Trends in Analytical Chemistry.
Scognamiglio, V., Antonacci, A., Arduini, F., Moscone, D., Campos, E. V., Fraceto, L. F., & Palleschi, G. (2019). An eco-designed paper-based algal biosensor for nanoformulated herbicide optical detection. Journal of Hazardous Materials.
Arduini, F., Scognamiglio, V., Cinti, S., Amine, A., Antonacci, A., Vasiljevic, J., … & Palleschi, G. (2019). Enzyme‐Based Materials. Handbook of Smart Materials in Analytical Chemistry, 179-209.
Antonacci, M. D. Lambreva, F. Arduini, D. Moscone, G. Palleschi, V. Scognamiglio* (2018). A whole cell optical bioassay for the detection of chemical warfare mustard agent simulants. Sensors and actuators B: Chemical 257, 658-665.
Pagliarini, D. Neagu, V. Scognamiglio, S. Pascale, G. Scordo, G. Volpe, E. Delibato, E. Pucci, A. Notargiacomo, M. Pea, D. Moscone, F. Arduini* (2018). Treated gold screen-printed electrode as disposable platform for label free immunosensing of Salmonella Typhimurium. Electrocatalysis, pp. 1-7.
Antonacci, F. Arduini, V. Scognamiglio* (2018). Vanguard Nano(bio)sensor Technologies Fostering the Renaissance of Agriculture, in Emerging Trends, in Agri-Nanotechnology (Eds. H.B. Singh, S. Mishra, L.F. Fernandes Fraceto, Renata de Lima) CABI Book, UK, https://www.cabi.org/bookshop/book/9781786391445
Arduini*, V. Scognamiglio, S. Cinti, A. Amine, A. Antonacci, J. Vasiljevic, G. Favaretto, D. Moscone, G. Palleschi (2018). Enzyme-based materials, in Handbook of Smart Materials in Analytical Chemistry (vol. 1) (Eds. Miguel de la Guardia and Francesc A. Esteve-Turrillas) WILEY
https://www.wiley.com/en-us/Handbook+of+Smart+Materials+in+Analytical+Chemistry-p-9781119422617
Arduini, F., Cinti, S., Scognamiglio, V., Moscone, D. (2017). Based Electrochemical Devices in Biomedical Field: Recent Advances and Perspectives. Comprehensive Analytical Chemistry.
Arduini, F., Cinti, S., Scognamiglio, V., Moscone, D., Palleschi, G. (2017). How cutting-edge technologies impact the design of electrochemical (bio) sensors for environmental analysis. A review. Analytica Chimica Acta.
Arduini, F., Forchielli, M., Scognamiglio, V., Nikolaevna, K. A., Moscone, D. (2016). Organophosphorous Pesticide Detection in Olive Oil by Using a Miniaturized, Easy-to-Use, and Cost-Effective Biosensor Combined with QuEChERS for Sample Clean-Up. Sensors, 17(1), 34.
Scognamiglio, V., Antonacci, A., Lambreva, M. D., Arduini, F., Palleschi, G., Litescu, S. C., Johanningmeier, U., Rea, G. (2016). Application of Biosensors for Food Analysis. Food Safety: Innovative Analytical Tools for Safety Assessment, 395, 395.
Antonacci, A., Arduini, F., Moscone, D., Palleschi, G., & Scognamiglio, V. (2016). Commercially Available (Bio) sensors in the Agrifood Sector. Comprehensive Analytical Chemistry.
Scognamiglio, V., Antonacci, A., Patrolecco, L., Lambreva, M. D., Litescu, S. C., Ghuge, S. A., & Rea, G. (2016). Analytical tools monitoring endocrine disrupting chemicals. TrAC Trends in Analytical Chemistry, 80, 555-567.
Zobnina, V., Lambreva, M. D., Rea, G., Campi, G., Antonacci, A., Scognamiglio, V., Giardi, M.T., Polticelli, F. (2016). The plastoquinol–plastoquinone exchange mechanism in photosystem II: insight from molecular dynamics simulations. Photosynthesis Research, 1-16.
Scognamiglio, V., Rea, G., Arduini, F., & Palleschi, G. (2016). Biosensors for Sustainable Food-New Opportunities and Technical Challenges (Vol. 74). Elsevier.
Arduini, F., Cinti, S., Scognamiglio, V., & Moscone, D. (2016). Nanomaterials in electrochemical biosensors for pesticide detection: advances and challenges in food analysis. Microchimica Acta, 1-21.
Fraceto, L. F., Grillo, R., De Medeiros, G. A., Scognamiglio, V., Rea, G., Bartolucci, C. (2016). Nanotechnology in Agriculture: which innovation potential does it have?. Frontiers in Environmental Science, 4, 20.
Arduini, F., Scognamiglio, V., Moscone, D., Palleschi, G. (2016). Electrochemical Biosensors for Chemical Warfare Agents. In Biosensors for Security and Bioterrorism Applications (pp. 115-139). Springer International Publishing.
Arduini, F., Neagu, D., Pagliarini, V., Scognamiglio, V., Leonardis, M. A., Gatto, E., Amine, A., Palleschi, G., Moscone, D. (2016). Rapid and label-free detection of ochratoxin A and aflatoxin B 1 using an optical portable instrument. Talanta, 150, 440-448.
Scognamiglio V., Antonacci A., Lambreva M.D., Litescu S.C., Rea G. (2015) Synthetic biology and biomimetic chemistry as converging technologies fostering a new generation of smart biosensors. Biosensor and Bioelectronics 74:1076-1086.
F. Arduini, D. Neagu, V. Scognamiglio, S. Patarino, D. Moscone, G. Palleschi (2015) Automatable Flow System for Paraoxon Detection with an Embedded Screen-Printed Electrode Tailored with Butyrylcholinesterase and Prussian Blue Nanoparticles. Chemosensors 3 (2), 129-145.
Arduini F., Scognamiglio V., Covaia C., Amine A., Moscone D., Palleschi, G. (2015). A choline oxidase amperometric bioassay for the detection of mustard agents based on screen-printed electrodes modified with prussian blue nanoparticles. Sensors, 15(2), 4353-4367.
Scognamiglio V., Arduini F., Palleschi G., Rea G. (2014) Biosensing technology for a sustainable food safety. Trends in Analytical Chemistry DOI: 10.1016/j.trac.2014.07.007.
Paul J.D. Janssen, Maya D. Lambreva, Nicolas Plumeré, Cecilia Bartolucci, Amina Antonacci, Katia Buonasera, Raoul Frese, Viviana Scognamiglio, Giuseppina Rea (2014) Photosynthesis at the forefront of a sustainable life. Frontiers in Chemistry: Agricultural Biological Chemistry. Front. Chem. 2:36. doi:10.3389/fchem.2014.00036.
Lambreva M. D., Russo D., Polticelli F., Scognamiglio Viviana, Antonacci A., Zobnina V., Campi G., Rea G. (2014) Structure/function/dynamics of Photosystem II plastoquinone binding sites. Current Protein and Peptide Science 15(4): 285–295.
Scognamiglio V, Stano P, Polticelli F, Antonacci A, Lambreva MD, Pochetti G, Giardi MT, Rea G. (2013) Design and biophysical characterization of atrazine sensing peptides mimicking the Chlamydomonas reinhardtii plastoquinone binding niche. Phys.Chem. Chem. Phys. 15, 13108-13115.
Viviana Scognamiglio (2013) Nanotechnology in glucose monitoring: Advances and challenges in the last 10 years. Biosensors and Bioelectronics. 47: 12-25
Viviana Scognamiglio, Italo Pezzotti, Gianni Pezzotti, Juan Cano, Ivano Manfredonia, Katia Buonasera, Giuseppe Rodio, Maria Teresa Giardi (2012) A new embedded biosensor platform based on Micro-Electrodes array (MEA) technology. Sensors & Actuators B: Chemical. 176: 275–283
Viviana Scognamiglio, Italo Pezzotti, Gianni Pezzotti, Juan Cano, Ivano Manfredonia, Katia Buonasera, Fabiana Arduinic, Danila Moscone, Giuseppe Palleschi, Maria Teresa Giardi (2012) Towards an integrated biosensor array for simultaneous and rapid multi-analysis of endocrine disrupting chemicals. Analytica Chimica Acta. 751: 161-70
V Scognamiglio, G Pezzotti, I Pezzotti, J Cano, K Buonasera, D Giannini, MT Giardi (2010) Biosensors for effective environmental and agrifood protection and commercialization: from research to market. Microchimica Acta 170: 215-225
K Buonasera, G Pezzotti, V Scognamiglio, A Tibuzzi, MT Giardi(2010) A new platform of biosensors for pre-screening of pesticide residues to support laboratory analyses. Journal of Agricultural and Food Chemistry 58: 5982-5990
Rea G, Polticelli F, Antonacci A, Scognamiglio V, Katiyar P, Kulkarni SA, Johanningmeier U, Giardi MT (2009) Structure-based design of novel Chlamydomonas reinhardtii D1-D2 photosynthetic proteins for herbicide monitoring. Protein Sci 18(10):2139-51
MT Giardi, V Scognamiglio, G Rea, G Rodio, A Antonacci, M Lambreva, G Pezzotti, U Johanningmeier (2009) Optical biosensors for environmental monitoring based on computational and biotechnological tools for engineering the photosynthetic D1 protein of Chlamydomonas reinhardtii. Biosens Bioelectron 25(2):294-300
V Scognamiglio, D Raffi, M Lambreva, G Rea, A Tibuzzi, G Pezzotti, U Johanningmeier, MT Giardi (2009) Chlamydomonas reinhardtii genetic variants as probes for fluorescence sensing system in detection of pollutants. Anal Bioanal Chem. Jun 394(4):1081-1087
Scognamiglio V, Scirè A, Aurilia V, Staiano M, Crescenzo R, Palmucci C, Bertoli E, Rossi M, Tanfani F, D’Auria S. (2007) A strategic fluorescence labelling of D-galactose/D-glucose-binding protein from E. coli for a better understanding of the protein structural stability and dynamics. J Proteome Res. 6(11): 4119-26.
Scognamiglio V, Aurilia V, Ringhieri P, Iozzino L, Tartaglia M, Staiano M, Zeni L, Cennamo N, Vitale A, Rossi M, D’Auria S. (2007) The Galactose/Glucose-binding protein from Escherichia coli as probe for a non-consuming glucose implantable fluorescence biosensor. Sensors Journal 7: 2484-2491.
Staiano M, Scognamiglio V, Mamone G, Rossi M, Parracino A, Rossi M, D’Auria S. (2006) Glutamine-binding protein from Escherichia coli specifically binds a wheat gliadin peptide. 2. Resonance energy transfer studies suggest a new sensing approach for an easy detection of wheat gliadin. J Proteome Res 5(9): 2083-2086.
D’Auria S, Staiano M, Varriale A, Scognamiglio V, Rossi M, Parracino A, Campopiano S, Cennamo N, Zeni L. (2006) The odorant-binding protein from Canis familiaris: purification, characterization and new perspectives in biohazard assessment. Protein Pept Lett 13(4): 349-352.
D’Auria S, Ausili A, Marabotti A, Varriale A, Scognamiglio V, Staiano M, Bertoli E, Rossi M, Tanfani F. (2006) Binding of glucose to the D-galactose/D-glucose-binding protein from Escherichia coli restores the native protein secondary structure and thermostability that are lost upon calcium depletion. J Biochem (Tokyo) 139(2): 213-221.
De Stefano L, Rotiroti L, Rendina I, Moretti L, Scognamiglio V, Rossi M, D’Auria S. (2006) Porous silicon-based optical microsensor for the detection of L-glutamine. Biosens Bioelectron 21(8): 1664-1667.
Herman P, Vecer J, Barvik I Jr, Scognamiglio V, Staiano M, de Champdore M, Varriale A, Rossi M, D’Auria S. (2005) The role of calcium in the conformational dynamics and thermal stability of the D-galactose/D-glucose-binding protein from Escherichia coli. Proteins 61(1): 184-195.
Staiano M, Scognamiglio V, Rossi M, D’Auria S, Stepanenko OV, Kuznetsova IM, Turoverov KK. (2005) Unfolding and refolding of the glutamine-binding protein from Escherichia coli and its complex with glutamine induced by guanidine hydrochloride. Biochemistry 44(15): 5625-5633.
Stepanenko OV, Kuznetsova IM, Turoverov KK, Scognamiglio V, Staiano M, D’Auria S. (2005)The structure and stability of the glutamine-binding protein from Escherichia coli and its complex with glutamine. Tsitologiia (Russia) 47(11): 988-1006.
Kuznetsova IM, Stepanenko OV, Turoverov KK, Staiano M, Scognamiglio V, Rossi M, D’Auria S. (2005) Fluorescence properties of glutamine-binding protein from Escherichia coli and its complex with glutamine. J Proteome Res 4(2): 417-423.
D’Auria S, Scire A, Varriale A, Scognamiglio V, Staiano M, Ausili A, Marabotti A, Rossi M, Tanfani F. (2005) Binding of glutamine to glutamine-binding protein from Escherichia coli induces changes in protein structure and increases protein stability. Proteins 58(1): 80-87.
Herman P, Vecer J, Scognamiglio V, Staiano M, Rossi M, D’Auria S. (2004) A recombinant glutamine-binding protein from Escherichia coli: effect of ligand-binding on protein conformational dynamics. Biotechnol Prog 20(6): 1847-1854.
Staiano M, Sapio M, Scognamiglio V, Marabotti A, Facchiano AM, Bazzicalupo P, Rossi M, D’Auria S. (2004) A thermostable sugar-binding protein from the Archaeon Pyrococcus horikoshii as a probe for the development of a stable fluorescence biosensor for diabetic patients. Biotechnol Prog 20(5): 1572-1577.
Scognamiglio V, Staiano M, Rossi M, D’Auria S. (2004) Protein-based biosensors for diabetic patients. J Fluoresc 14(5): 491-498.