Alessandro Pesaresi


Alessandro Pesaresi

Alessandro Pesaresi


Phone1:+39 040 375 7520 (Off.) /

Phone2:+39 040 375 7521 / 7536 / 7537 (Lab.)


Address: Istituto di Cristallografia - C.N.R. Sede Secondaria di Trieste,

Area Science Park – Basovizza

Edificio Q1, Stanza 105A

Strada Statale 14, Km. 163.5

I-34149 Trieste – Italy





Present position :

- Staff Researcher


Short CV :

2011: Permanent Position as Researcher, IC CNR, Trieste Outstation.
2008-2011: Contract Researcher in Structural Biology, IC CNR, Trieste Outstation.
2006-2008: Postdoctoral Research Associate in Protein Crystallography, Albert Einstein College of Medicine, Bronx, NY, USA.
2005-2006: Postdoctoral Fellowship in Protein Crystallography, "Crystallography Excellence Center", University of Trieste.
2005: PhD in Structural and Functional Genomic, "International School for Advanced Studies", Trieste.
2000: Laurea diploma in Biology, University of Bologna.


Research Activity :

-Structural studies of microbial enzymes involved in polysaccharides degradation and processing
-Targeting mechanisms of Pseudomonas aeruginosa pathogenesis
-Structural studies of novel oxime as blood-brain barrier penetrating Acetylcholinesterase reactivators


Selected publications :

1. Pesaresi A., Lamba D. "Insight into the fatty acid chain length specificity of the carboxylesterase PA3859 from Pseudomonas aeruginosa: A combined structural, biochemical and computational study. Biochimie 92, 1787-92 (2010)

2. Marri L, Pesaresi A, Valerio C, Lamba D, Pupillo P,
Trost P, Sparla F. "In vitro characterization of Arabidopsis CP12 isoforms reveal
common biochemical and molecular properties". Journal of Plant Physiology 167, 969-50 (2010).

3. Campagnolo M, Pesaresi A, Zelezetsky I, Geremia S, Randaccio L, Bisca A, Tell G. "Structural studies on Pax-8 domain/DNA complex". J Biomol Struct Dyn 24, 429-41 (2007).

4. Pesaresi A, Lamba D. "Crystallization, X-ray diffraction analysis and
phasing of the carboxylesterase PA3859 from Pseudomonas aeruginosa". Biochimica et
Biophysica Acta 1752, 197-201 (2005).

5. Pesaresi A, Devescovi G, Lamba D, Venturi V, Degrassi G.
" Isolation, characterization and eterologous expression of a carboxylesterase from of
Pseudomonas aeruginosa PAO1". Current Microbiology 50, 102-9 (2005).



Last Updated (Friday, 22 April 2016 14:16)