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SDS

SDS

 TITLE:  Drug Design in a rare disease like the Shwachman-Diamond Syndrome: conformational study of the protein EFL1 and the screening of small organic molecules capable of modulating its function SDS DISEASE     FINANCING SCHEME: ...

MATERIAL SCIENCE – IC TRIESTE

MATERIAL SCIENCE – IC TRIESTE

 DESCRIPTION:  X-ray diffraction measurements with synchrotron light from samples of interest for materials science, in order to characterize their crystallinity, type of disorder, preferential orientation, crystallite dimensions, multifasicity and phase transitions as a function...

STRUCTURAL BIOLOGY – IC TRIESTE

STRUCTURAL BIOLOGY – IC TRIESTE

 DESCRIPTION:  The structural biology group in Trieste is strongly focused on the structure-activity-function relationship in proteins relevant to biomedicine and biotechnology, aiming at the understanding of the molecular determinants underlying their biological activities. Among...

BIOPHYSICAL CHARACTERIZATION FACILITY – IC TRIESTE

BIOPHYSICAL CHARACTERIZATION FACILITY – IC TRIESTE

 DESCRIPTION:  The biophysical characterization laboratory is one of the facilities used by the structural biology group in Trieste. The facility is used for functional studies on proteins, which are then correlated with the results...

BIOLAB – IC TRIESTE

BIOLAB – IC TRIESTE

 DESCRIPTION:  The molecular biology laboratory (Biolab) is one of the core facilities in use from the structural biology group in Trieste. The preparation of the protein samples used in our structural and functional investigations,...

CRYSTALLIZATION – IC TRIESTE

CRYSTALLIZATION – IC TRIESTE

 DESCRIPTION:  The crystallization facility is organized at two different sites: The high-throughput screenining core facility is shared with the Structural Biology Laboratory at ELETTRA-Sincrotrone Trieste. Two instruments are used for nanoliters liquid handling for...

XRD1 – IC TRIESTE

XRD1 – IC TRIESTE

 DESCRIPTION:  The hard X-ray diffraction beamline XRD1 at Elettra was designed for macromolecular crystallography, but its characteristics allow performing a wide variety of experiments. The source is a multipolar wiggler with a useful energy...