Giovanni Luca Cascarano Personal Page

Present position : Senior Researcher

Address and Email :

Tel. +39 080 5929145
Fax +39 080 5929147
E-mail : gianluca.cascaranoATic.cnr.it
Address :
Via Amendola 122/o – 70126 Bari

Short CV :

1979: Computer Science Diploma
1989: PhD degree
1989-1994: Five years contract as researcher at IRMEC (now IC) – CNR
1994-1998: Five years contract as head research at IRMEC (now IC) – CNR
1998-2001: Staff researcher at IRMEC (now IC) – CNR
2001: Staff senior researcher at at IRMEC (now IC) – CNR

Organization of events:

– 3-rd National School on Neutron and X-Ray Diffraction 26th october- 5th november 1992.
– Fourth SIR workshop 5th -7 of april 1993
– Fifth SIR workshop 17-27th of december 1996
– XX National meeting of the Associazione Italiana di Cristallografia 19th – 22nd of september 2000.
– EuroConference on Phasing Biological Macromolecules (PHABIO) 23rd -27th of june 2001.
– First precession electron diffraction user meeting 8th – 9th of may 2008.

Scientific interests:

The main interest is the field of the crystallographic methodologies development. Such methodologies are of fundamental importance for the studies of the crystal structures and the related properties: drugs, proteins, new material of technological interest can be investigated using crystallographic methods.

Research Activity :

The developed theories on crystallographic methodologies and related applications have produced more than 100 papers on international journals. The developed theories have been implemented in scientific software for the automatic solution of crystal structures using single crystal data (Sir92, Sir97, Sir2002, Sir2004, Sir2008, il Milione) and powder data (SirPow, Expo). This software is freely distributed to the scientific community and it is used in hundreds of labs all over the world. Power, easy of use, friendly Graphical User Interface made this software very popular and used by crystallographers.

Selected publications :

– A. Altomare, G. Cascarano, C. Giacovazzo, A. Guagliardi, M.C. Burla, G. Polidori, M. Camalli (1994)
SIR92 – a program for automatic solution of crystal structures by direct methods
J. Appl. Cryst. 27,435.
– R. Caliandro, G. Cascarano, C. Giacovazzo & A. Melidoro (1997)
Direct Methods versus Electron Diffraction: the first experiences by SIR97
D.L. Dorset et al. (eds.), Electron Crystallography, 261-272.
– M.C.Burla, B. Carrozzini, G.L. Cascarano, L. De Caro, C. Giacovazzo, G. Polidori (2003)
Ab initio protein phasing at 1.4Å resolution
Acta Cryst A59,245-249.
– R.Caliandro, B. Carrozzini, G.L. Cascarano, L. De Caro, C. Giacovazzo, A.M. Mazzone, D. Siliqi (2006)
Molecular replacement: the approach of the program REMO
J. Appl. Cryst. 39,185-193.
– M.C.Burla, R. Caliandro, M. Camalli, B. Carrozzini, G.L. Cascarano, L. De Caro, C. Giacovazzo, G. Polidori D. Siliqi, R. Spagna (2007)
IL MILIONE: a suite of computer programs for crystal structure solution of proteins
J. Appl. Cryst. 40,609-613.