Synthesis laboratory

Automated Microwave Peptide Synthesizer

Two microwave-assisted peptide synthesizers (Liberty, CEM) are operating at the IC synthesis laboratory in Catania, capable of satisfying the growing demand for synthetic peptides. Microwave-assisted solid-phase peptide synthesis (MW-SPPS) is a very high-speed, high-efficiency technology widely used for research, recently also available on a kilo scale. MW-SPPS is advantageous in terms of yield, purity, time savings and solvent consumption. The reaction temperature in the mono-modal cavity, monitored by an internal fiber optic sensor, makes the procedure highly reproducible. MW-SPPS can be a reliable technological support for the rapid production of difficult peptide sequences and peptide conjugates, with an incomparable quality.