Istituto di Cristallografia - CNR

Amyloid-Beta and Alzheimer’s Disease: Molecular Updates from Physiology to Pathology

Alzheimer’s disease (AD) represents one of the most challenging disorders, and despite having been widely studied since its first identification, resolutive treatments are still far out of reach. The current knowledge of this progressive, incurable disease involves many aspects of its pathology, even those not closely related to the main hallmarks of AD, Amyloid-beta (Aβ) and Tau. However, despite the emergence a new, complex perspective of AD as a multifactorial disease, the role of Aβ and Tau remains central. Looking at the current pipeline of AD drug development, great efforts are being made to move from symptomatic to disease-modifying treatments

Anno
2023
Rivista
International journal of molecular sciences (Print) 24
Impact factor
6.208
AMBITI DI RICERCA
KEYWORDS
Autori
Giuffrida Maria Laura
Autori IC CNR