Institute of Crystallography - CNR

Wide and Small Angle X-ray Scattering for the structural characterization of fibers

X-ray structural investigations of nanofibrous structures with natural or synthetic macromolecules as building blocks to fabricate smart materials with tunable specific properties linked to their hierarchical order

Wide-Angle (WAXS) and Small-Angle (SAXS) X-ray Scattering are techniques available at the X-ray MicroImaging Laboratory (XMI-Lab) of the Institute of Crystallography in Bari equipped with by a table-top high brilliance (synchrotron class) X-ray micro-source.
The studies on nanofibrous materials are mainly focused, until now, on: (i) natural polymeric fibers (such as type I collagen), (ii) silk fibroin from Bombix Mori, (iii) cellulose
(iv) engineered fibers, (peptide-based supramolecular architectures).
SAXS and WAXS provide with micrometric spatial resolution the molecular and supramolecular structure of fibrillar materials. The fibers can be studied in the solid state or dispersed in solutions.

Reference works

– Carlo Diaferia, Flavia Anna Mercurio, Cinzia Giannini, Teresa Sibillano, Giancarlo Morelli, Marilisa Leone & Antonella Accardo, Self-assembly of PEGylated tetra-phenylalanine derivatives: structural insights from solution and solid state studies, Scientific Reports volume 6, Article number: 26638 (2016)
– A. Terzi, E. Storelli, S. Bettini, T. Sibillano, D. Altamura, L. Salvatore, M. Madaghiele, A. Romano, D. Siliqi, M. Ladisa, L. De Caro, A. Quattrini, L. Valli, A. Sannino, C., Giannini, Sci Rep., 2018, 8, 1, 1429
– Rizzo G.; Lo Presti M.; Giannini C.; Sibillano T.; Milella A.; Matzeu G.; Musio R.; Omenetto F.G.; Farinola G.M., Silk Fibroin Processing from CeCl3 Aqueous Solution: Fibers Regeneration and Doping with Ce(III), Macromolecular Chemistry and Physics 221(13), (2020)
– Teresa Sibillano, Alberta Terzi, Liberato De Caro, Massimo Ladisa, Davide Altamura, Anna Moliterni, Rocco Lassandro, Francesco Scattarella, Dritan Siliqi and Cinzia Giannini, Wide Angle X-Ray Scattering to Study the Atomic Structure of Polymeric Fibers, Crystals 2020, 10(4), 274 (2020)