This research activity involves the development of "green" chemoenzymatic and organocatalytic methods for the preparation of chiral molecules and active pharmaceutical ingredients (APIs) that have a positive impact on the...
Structural characterization of bio-macromolecules in the presence of pharmacological/biotechnological-interesting compounds to provide useful information for the optimization process of the latter ones as well as the identification of the molecular...
Development, software implementation and application of advanced crystallographic methodologies to optimise and automatise the crystal structure characterization process through X-ray diffraction from polycrystalline materials (micro and nanocrystalline) of various types...
Studies at the molecular level have highlighted the multifactoriality of chronic-degenerative diseases, to whose onset the following contribute: chronic inflammatory state, genome instability, excessive ROS production, alterations in morphology and...
Characterize materials (surfaces, soft matter, powders) by hard X-ray diffraction from synchrotron light source: • recognition of phases • indexing and identification of orientations with respect to surfaces • profile...
Nanomaterials with extraordinary optical properties are organized on transparent, reflective, or flexible substrates for the development of active and multifunctional sensing platforms. Accordingly, nanoparticle-based surfaces and metasurfaces, suitably functionalized, work...
The research activity focuses on the synthesis and the study of peptides that bind oncogenic pre-miRNAs for therapeutic purposes, antimicrobial peptides replacing the antibiotics and peptides based biosensors to develop...
The general objective is the identification and verification of new molecular mechanisms that regulate the molecular targeting to systems at different complexity, in order to modulate their biological and genetic...
PNAs are nucleic acid analogues which have implemented affinity, specificity and are resistant to enzymatic degradation. All these features make PNA an outstanding candidate as antisense, antigene, miRNA targeting molecules...
Study of interest materials for cultural heritage using non-destructive and non-invasive analytical and imaging techniques based on X-ray and UV-VIS-IR radiation to support the study and conservation of historical and...
