Galectins are an ancient family of lectins characterized by the specific binding of ?-galactosides through evolutionarily conserved sequence elements of the carbohydrate recognition domain. Interest in this protein family is...
The endocannabinoid system (ECS) plays a very important role in numerous physiological and pharmacological processes, such as those related to the central nervous system (CNS), including learning, memory, emotional processing,...
In this work it is demonstrated that enantiomerically enriched N-alkyl 2-oxazolinylazetidines undergo exclusive alpha-lithiation, and that the resulting lithiated intermediate is chemically stable but configurationally labile under the given experimental...
Over the years, cyclodextrin uses have been widely reviewed and their proprieties provide a very attractive approach in different biomedical applications. Cyclodextrins, due to their char-acteristics, are used to transport...
A new parasitic, mixed-field, neutron-dominated irradiation station has been recently commissioned at the European Laboratory for Particle Physics (CERN). The station is installed within the neutron time-of- flight (n_TOF) facility,...
Nerve growth factor (NGF), the prototypical neurotrophic factor, is involved in the maintenance and growth of specific neuronal populations, whereas its precursor, proNGF, is involved in neuronal apoptosis. Binding of...
Despite recent advances, the crystal structure solution process from powder X-ray diffraction (PXRD) data is still a challenging task. In this article, we present case studies of structure solutions using...
Cannabinoid type 2 receptor (CB2R), belonging to the endocannabinoid system, is overexpressed in pathologies characterized by inflammation, and its activation counteracts inflammatory states. Fatty acid amide hydrolase (FAAH) is an...
The bioavailability of copper (Cu) in human cells may depend on a complex interplay with zinc (Zn) ions. We investigated the ability of the Zn ion to target the human...
Hole transporting materials (HTMs) Way a crucial role in developing highly efficient and stable perovskite solar cells (PSCs). Their function is to extract and transport hole carriers, but at the...
