In the last two decades, the amyloid hypothesis, i.e., the abnormal accumulation of toxic A? assemblies in the brain, has been considered the mainstream concept sustaining research in Alzheimer's Disease...
A one dimensional (1D) perovskite-type (C6H7NBr)3[CdBr5] (abbreviated 4-BAPC) was synthesized by slow evaporation at room temperature (RT). 4-BAPC crystalizes in the monoclinic system with the space group P21/c. The 1D...
The reactivity of 2-alkynylbenzoic acids under PdI2/KI-catalyzed oxidative alkoxycarbonylation conditions, with oxygen (from air) as external oxidant and an alcohol as external nucleophile, has been studied. It was found that...
High-dimensionality Ruddlesden-Popper (RP) perovskites, with general formula R(2)A(n-1)B(n)X(3n+1) and high n values (n >= 5), are regarded as viable materials for photovoltaics because they feature higher stability if compared to...
Diffusion tensor imaging (DTI) has demonstrated the potential to assess the pathophysiology of mild traumatic brain injury (mTBI) but correlations of DTI findings and pathological changes in mTBI are unclear....
In cancer microenvironment, aberrant glycosylation events of ECM proteins and cell surface receptors occur. We developed a protocol to generate 3D bioprinted models of colorectal cancer (CRC) crosslinking hyaluronic acid...
An eco-friendly metal-free protocol was developed for the regioselective synthesis of densely functionalized 1,2,3-triazoles through a 1,3-dipolar cycloaddition reaction of alkanone enolates with azides performed in the environmentally responsible choline...
Date: 07 /03/2023 New frontiers of biophysics to challenge biomolecules involved in the molecular mechanism of diseases.
SPOKE 7 (https://www.supercomputing-icsc.it/en/spoke-7-materials-molecular-sciences-en/) Design, implementation, maintenance, and dissemination of enabling technologies for the high-performance numerical simulation of materials and molecular systems CONTEXT From the stone to the silicon age, human...
Alzheimer’s disease (AD) is a chronic neurodegenerative disorder leading to memory loss and progressive decline in cognitive ability. The main component of these plaques is the 40–42-amino acid residue amyloid-β...
