Purpose Translocator protein 18-kDa (TSPO) positron emission tomography (PET) is a valuable tool to detect neuroinfammed areas in a broad spectrum of neurodegenerative diseases. However, the clinical application of second-generation...
Mutations in Cu/Zn Superoxide Dismutase (SOD1) gene represent one of the most common causes of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disorder that specifically affects motor neurons (MNs). The...
Experiments with cell cultures and animal models have provided solid support for the assumption that Nerve Growth Factor (NGF) plays a key role in the regulation of neuronal cell survival...
Using a combined theoretical and experimental approach, a mechanistic understanding of the interactions and pseudocapacitance of different quinone- coupled viologen and pyridiniumium molecules sandwiched between titanium carbide (Ti3C2Tx) MXene layers...
Alzheimer's disease (AD) is a progressive neurodegenerative condition affecting people in the elderly. Targeting aggregation of ?-amyloid peptides (A?) is considered a promising approach for the therapeutic treatment of the...
In the few last years, nanosystems have emerged as a potential therapeutic approach to improve the efficacy and selectivity of many drugs. Cyclodextrins (CyDs) and their nanoparticles have been widely...
A systematic study is conducted to compare the performances and stability of active layers employing a high performance electron donor (PBDB-T) combined with state-of-the-art fullerene (PC71BM), nonfullerene (ITIC), and polymer...
The recent outbreak of COVID-19 has created much inconvenience and fear that the virus can seriously affect humans, causing health hazards and death. This pandemic has created much worry and...
Drug-induced blockade of the human ether-à-go-go-related gene (hERG) channel is today considered the main cause of cardiotoxicity in postmarketing surveillance. Hence, several ligand-based approaches were developed in the last years...
The Coronavirus disease 2019 (COVID-19) emergency has demonstrated that the utilization of face masks plays a critical role in limiting the outbreak. Healthcare professionals utilize masks all day long without...
