Quantitative and multi-length scale structural imaging of biotissues is performed through the SAXS/WAXS/absorption contrast detection. Crystalline order modifications at the atomic and nano scale are related to physio-pathologic conditions of...
Studies on the bone matrix biomineralization and genetic and epigenetic regulation are performed in model systems and biologic fluids collected from astronauts before, during and after space flights, to develop...
The activity of the SPR laboratory is focused on the characterization of the biomolecular interactions, which allow to measure the kinetic constants, the affinity and the stoichiometry of the binding....
The experimental study of the structural dynamics of crystalline or amorphous compounds is addressed using X-ray experiments in situ / operando and analyzing the data collected according to multivariate analysis...
The activity aims to obtain structural models with atomic or quasi-atomic resolution of proteins of medical, pharmaceutical and biotechnological interest by applying crystallographic methodologies and techniques, and to simulate their...
We study dynamic disorder, playing a fundamental role in functionality of complex matter, by applying physical statistics to big data set collected by high spatiotemporal resolution probes. Complex matter can...
The activities deal with the quantitative analysis of biological processes and bio/molecular interactions useful for the development of bio/sensors for monitoring environmental pollutants and food quality and safety. Concomitantly, instrumentation...
Synthesis (solid state, room temperature) of calcium phosphates such as apatite Ca5(PO4)3(F, Cl, OH) o tricalcium phosphate Ca3(PO4)3 and their structural characterization through techniques of X-ray diffraction, vibrational spectroscopy such...
Geomaterials such as phosphates, silicates, borates, are carefully investigated through crystal-chemical characterization based on XRD, FTIR, Raman and SEM-EDS microscopy. The obtained results make up the basis for the development...
The alteration of proteostasis, i.e the control of the proteome integrity, is the basis of many diseases (eg cancer, Alzheimer's, Parkinson's and diabetes). The research activity is aimed at the...
