The general objective is the identification and verification of new molecular mechanisms that regulate the molecular targeting to systems at different complexity, in order to modulate their biological and genetic...
PNAs are nucleic acid analogues which have implemented affinity, specificity and are resistant to enzymatic degradation. All these features make PNA an outstanding candidate as antisense, antigene, miRNA targeting molecules...
Study of interest materials for cultural heritage using non-destructive and non-invasive analytical and imaging techniques based on X-ray and UV-VIS-IR radiation to support the study and conservation of historical and...
Quantitative and multi-length scale structural imaging of biotissues is performed through the SAXS/WAXS/absorption contrast detection. Crystalline order modifications at the atomic and nano scale are related to physio-pathologic conditions of...
Studies on the bone matrix biomineralization and genetic and epigenetic regulation are performed in model systems and biologic fluids collected from astronauts before, during and after space flights, to develop...
The activity of the SPR laboratory is focused on the characterization of the biomolecular interactions, which allow to measure the kinetic constants, the affinity and the stoichiometry of the binding....
The experimental study of the structural dynamics of crystalline or amorphous compounds is addressed using X-ray experiments in situ / operando and analyzing the data collected according to multivariate analysis...
The activity aims to obtain structural models with atomic or quasi-atomic resolution of proteins of medical, pharmaceutical and biotechnological interest by applying crystallographic methodologies and techniques, and to simulate their...
We study dynamic disorder, playing a fundamental role in functionality of complex matter, by applying physical statistics to big data set collected by high spatiotemporal resolution probes. Complex matter can...
The activities deal with the quantitative analysis of biological processes and bio/molecular interactions useful for the development of bio/sensors for monitoring environmental pollutants and food quality and safety. Concomitantly, instrumentation...
