Trieste
Responsabile di Sede: Alberto Cassetta
Contacts
alberto.cassetta@ic.cnr.it
(+39) 040 3757525
Address
Trieste
Strada Statale 14 km 163,5 - 34149 Basovizza – Trieste
STAFF
Laboratories
Biophysical CharacterizationThe Biophysical Characterization Laboratory houses a range of equipment for the analysis of the biophysical properties of proteins as well as intermolecular interactions. Techniques available include: • UV-visible spectrophotometry; • Dynamic Light Scattering for molecular size and polydispersity characterization; • Differential Scanning Fluorimetry to track protein thermal stability and to qualitatively study protein-ligand interaction in… |
Protein expression and purification laboratoryThe protein expression and purification laboratory provides highly pure protein samples suitable for structural studies. It employs traditional and Restriction free cloning techniques to construct expression plasmids, using a wide range of bacterial expression vectors to improve protein solubility. In case of insoluble proteins, refolding protocols can be routinary optimized. The lab specializes in parallel… |
Peptide synthesisThe peptide synthesis group of IC-CNR in Trieste cooperates with the peptide synthesis workstation of Department of Life Sciences (DSC) of University of Trieste, to achieve the synthesis and characterization of native and/or conformational constrained peptides. In particular, the research activity is focused on synthesis and analysis of native or modified antimicrobial peptides (AMP) containing… |
Beamline XRD1@ElettraXRD1 beamline is a multipurpose X ray diffraction beamline. The beamline source is a multipole wiggler producing an intense beam in the 4-21 keV energy range where a tunable double crystal monochromator allows for a rapid selection and optimization of the anomalous scattering condition. XRD1 allows for both macromolecular and small-molecules single-crystal crystal X ray… |