We propose a Shannon sampling based approach for the analysis of laboratory and synchrotron small-angle X-ray scattering (SAXS) data. This method avoids calculation of the pair distance distribution function P(r),...
Acetazolamide (AZA) is a validated carbonic anhydrase inhibitor (CAI) that has the potential for use in various therapeutic applications. Herein, we report a novel AZA-loaded biodegradable nanodelivery system that was...
Cardiac fibrosis is a pathological process associated with several heart diseases, characterized by extracellular matrix deposition by cardiac fibroblasts. Photothermal therapy is a minimally invasive medical treatment that uses nanomaterials...
The Se78(n,γ)Se79 cross section has a high impact on the abundances of Se78 produced during the slow neutron capture process (s process) in massive stars. A measurement of the Se78...
The electrocatalytic reduction reaction of CO2 (CO2RR) has been extensively studied, including on single-atom catalysts (SACs). However, a precise mechanistic understanding of the factors governing electron-transfer processes and Faradaic efficiency...
The energy dependence of the cross section of the (n,p) and (n,d) reactions on natC has been studied for the first time at the n_TOF facility at CERN, from the...
In this work, two new mixed-halide Thiele hydrocarbons were synthesized and characterized to elucidate the influence of halogenation patterns on their photophysical properties, addressing the role exerted by steric constraints...
Disorder is an intrinsic feature of all solids, from crystals of atoms to superlattices of colloidal nanoparticles. Unlike atomic crystals, in nanocrystal superlattices, a single misplaced particle can affect the...
A microwave-assisted esterification reaction to prepare hyaluronan-curcumin derivatives by employing a solvent-free process was developed. In particular, a solid-state strategy to react two molecules characterized by totally different solubility profiles...
: Achieving optimal target activity while maintaining synthetic accessibility and drug-likeness represents a major challenge in computational drug discovery. Existing de novo generative models often yield chemically invalid or synthetically...
