Mapping Amyloid-β post-translational modifications across deposits in Alzheimer’s disease: a neuropathological and functional analysis of nitration. Alzheimer’s disease is characterized by the accumulation of amyloid-β (Aβ) deposits that differ in...
Nucleic acids and their synthetic analogs have driven modern diagnostics of versatile platforms capable of detecting disease signatures with molecular precision [1]. Classical hybridization assays based on sequence complementarity have...
Human exploration beyond low Earth orbit poses unique health and operational challenges, with space radiation recognized as one of the most significant hazards. This comprehensive review examines the complex nature...
Apatite-type materials have attracted considerable attention due to their potential applications in optical, electronic, and energy devices. In this study, the synthesis and physicochemical characterization of the novel lacunary lead...
Brain natriuretic peptide (BNP) is a key biomarker for the diagnosis and monitoring of heart failure (HF), providing crucial information on cardiac function and disease progression. Conventional antibody-based detection methods,...
The reaction of the HS•/S•− radical (pKa ~3.4), generated selectively from H2S by γ-irradiated N2-flushed aqueous solutions at pH 5, with purine nucleosides (dG or dA), a 10-mer double-stranded oligodeoxynucleotide...
This work reports the development and analytical validation of FACILE 2.0, a portable multifunctional potentiostat designed for electrochemical measurements under both static and microfluidic configurations. The platform integrates a compact...
Microalgae represent some of the most promising eukaryotic platforms in biotechnology due to their rapid growth, simple cultivation requirements, reliance on sunlight as a primary energy source, and ability to...
Unveiling the fate of lipid crystalline structures in engineered emulsions during in vitro digestion
This study investigates how lipid crystalline structures in emulsions evolve during digestion, aiming to inform functional food design and potentially modulate lipid digestion. Using synchrotron-based X-ray diffraction, we monitored real-time...
: Four novel gold(I) N-heterocyclic carbene (NHC) complexes were synthesized and characterized; they are tuned in terms of the aromatic extension of the NHC scaffold and two of them contain...
