Noble metallic nanoparticles (NPs) have shown great potential in the field of sustainable energy. Gold nanorods (AuNRs), known for their size-dependent optical and electrical characteristics, are strong candidates for various...
Thioredoxin reductase 1 (TrxR1), a selenoprotein enzyme crucial for redox homeostasis in mammals, has emerged as a promising target for anticancer therapy. In this study, we present a non-covalent TrxR1...
Emerging evidence has demonstrated that cannabinoid receptor 2 (CB2) is involved in a number of diseases, such as neurodegenerative disorders and various types of cancer, making it an attractive pharmacological...
Developing user-friendly, high-performance sensing devices for nucleic acid detection is crucial for diagnostics, drug development, and personalized therapies. Nanotechnologies offer innovative solutions to meet this need, utilizing the organization and...
Lubeluzole is a neuroprotective agent displaying antimyotonic activity. Lubeluzole clinical development as an antiischemic drug was discontinued due to a lack of efficacy in human trials and possible cardiac toxicity....
The controlled assembly of nanocrystals (NCs) in 3D systems is an intriguing strategy to engineer innovative materials with advanced functionalities. Herein, undoped and manganese-doped cesium lead mixed halide perovskite NCs...
A new experimental area, the NEAR station, has recently been built at the CERN n_TOF facility, at a short distance from the spallation target (3 m). The new area, characterized...
Lysozyme-sensitive plasmonic hydrogel nanocomposite for colorimetric dry-eye inflammation biosensing
Detection of lysozyme levels in ocular fluids is considered crucial for diagnosing and monitoring various health and eye conditions, including dry-eye syndrome. Hydrogel-based nanocomposites have been demonstrated to be one...
Bioactive peptides (BPs)—short amino acid sequences with high selectivity, biocompatibility, and low toxicity—are increasingly important in therapeutics, nutrition, and biotechnology. Despite more than 80 peptide drugs in use and a...
The goal of this project is to synthesize novel dihydroisoindoline compounds by base-catalyzed intramolecular cyclization of ammonium salts containing 3-phenylprop-2-enyl group as a β,γ-unsaturated group, together with a 3-(4-methoxyphenyl)prop-2-ynyl group...
