Herein, we report the structure-based selection via molecular docking of four N-heterocyclic bis-carbene gold(I) complexes, whose potential as ligands for the hTel23 G-quadruplex structure has been investigated using circular dichroism...
Layered (2D) perovskites are an emerging attractive 2D system with enhanced stability to ambient conditions as opposed to their highly unstable three dimensional bulk counterpart. Their uniquely tuneable optical and...
To fully understand enzymatic dynamics, it is essential to explore the complete conformational space of a biological catalyst. The catalytic mechanism of the nickel-dependent urease, the most efficient enzyme known,...
In recent years, there has been a significant interest on sustainability and health-safety across various domains. Notably, many traditional chemicals employed in the preservation of Cultural Heritage pose environmental and...
Graphene nanoparticles (GNPs) can serve as a versatile platform for the development of drug-delivery systems by means of suitable functionalization strategies. By using a green physical method, we prepared GNPs...
: In recent years, nanoparticles based on cyclodextrins have been widely investigated, mainly for drug delivery. In this work, we synthesized nanoparticles with a hyaluronic acid backbone (11 kDa and...
The chemical and functional stability issues of halide perovskite films integrated in solar cells are presently catalyzing large interest in the scientific community. Strategies are explored in which A-site doping...
Clays have been exploited in the manufacture of diverse products from ceramics to paints, pharmaceuticals, plastics, cosmetics, and more. Thus, they can be used in many industrial applications, showing good...
A green synthetic protocol to add a chemical function to a fully deprotected peptide to obtain a bioactive and/or fluorescent-labeled conjugate is reported. A range of S-conjugation reactions promoted by...
: Developing sigma-1 receptor (S1R) modulators is considered a valuable therapeutic strategy to counteract neurodegeneration, cancer progression, and viral infections, including COVID-19. In this context, in silico tools capable of...
