L’Istituto di Cristallografia del Consiglio Nazionale delle Ricerche e l’Università Politecnico di Tirana (UPT), Albania intendono collaborare in ambito di ricerca al fine di beneficiare reciprocamente delle rispettive attrezzature, conoscenze...
Background: Humans are exposed to tens of thousands of chemical substances that need to be assessed for their potential toxicity. Acute systemic toxicity testing serves as the basis for regulatory...
Transmission Electron Microscopy (TEM) owes its success to the capability to investigate fundamental aspects of nature, answering the human need of knowledge necessary to understand unknown mechanisms and to find...
The conformational conversion of the cellular prion protein (PrP) into a misfolded, aggregated and infectious scrapie isoform is associated with prion disease pathology and neurodegeneration. Despite the significant number of...
While understanding the time evolution of Covid-19 pandemic is needed to plan economics and tune sanitary policies, a quantitative information of the recurrent epidemic waves is elusive. This work describes...
The crucial role of integrin in pathological processes such as tumor progression and metastasis formation has inspired intense efforts to design novel pharmaceutical agents modulating integrin functions in order to...
We present a combined real and reciprocal space structural and microstructural characterization of CeO nanoparticles (NPs) exhibiting different crystallite sizes; ~3 nm CeO NPs were produced by an inverse micellae...
Complex neurological disorders, including Alzheimer's disease, are one of the major therapeutic areas to which multitarget drug discovery strategies have been applied in the last twenty years. Due to the...
CsPbBrnanoclusters have been synthesized by several groups and mostly employed as single-source precursors for the synthesis of anisotropic perovskite nanostructures or perovskite-based heterostructures. Yet, a detailed characterization of such clusters...
A straightforward approach to new polycyclic heterocycles, 1H-benzo[4,5]imidazo[1,2-c][1,3]oxazin-1-ones, is presented. It is based on the ZnCl-promoted deprotective 6-endo-dig het-erocyclization of N-Boc-2-alkynylbenzimidazoles under mild conditions (CHCl, 40C for 3 h). The...