A recently developed synthetic protocol allowed for the functionalization of the active peptide A9 with a fluorogenic probe, which is useful for studying biomolecular interactions. Essentially, a nucleophilic attack on...
Galectins are soluble ?-D-galactoside-binding proteins whose implication in cancer progression and disease outcome makes them prominent targets for therapeutic intervention. In this frame, the development of small inhibitors that block...
Galectins (Gals) are small cytosolic proteins that bind ?-galactoside residues via their evolutionarily conserved carbohydrate recognition domain. Their dysregulation has been shown to be associated with many diseases. Consequently, targeting...
Drug-induced cardiotoxicity is a common side effect of drugs in clinical use or under postmarket surveillance and is commonly due to off-target interactions with the cardiac human-ether-a-go-go-related (hERG) potassium channel....
The 3D structure and surface characteristics of proteins and peptides are crucial for interactions with receptors or ligands and can be modified to some extent to modulate their biological roles...
Microalghe per il restauro In questo periodo storico di forte attenzione alla tutela dell’ambiente, è sempre più sentita la necessità di dover intraprendere azioni consapevoli e sostenibili. In tale contesto,...
Bando n. IC-004-2022-BA – PUBBLICA SELEZIONE PER IL CONFERIMENTO DI N° 1 ASSEGNO PROFESSIONALIZZANTE Prot. CNR-IC n. 0002236 del 06/10/2022 Prot. CNR-AMMCNT n. 0070519/2022 Scadenza del bando è il 24/10/2022...
Bando n. IC-005-2022-BA – PUBBLICA SELEZIONE PER IL CONFERIMENTO DI N° 1 ASSEGNO PROFESSIONALIZZANTE Prot. CNR-IC n. 0002237 del 06/10/2022 Prot. CNR-AMMCNT n. 0070525/2022 Scadenza del bando è il 24/10/2022...
Microgravity-induced bone loss is a major concern for space travelers. Ground-based microgravity simulators are crucial to study the effect of microgravity exposure on biological systems and to address the limitations...
The genus Orobanche includes about 100 different species. Among them, Orobanche crenata Forssk. (Orobanchaceae family), commonly known as broomrape, is a holoparasitic plant, noxious to legume crops that inhabits mainly...
