The URT is located within the Department of Environmental, Biological, and Pharmaceutical Sciences and Technologies at the University of Campania ‘Luigi Vanvitelli’. Active since February 2022, its research activities—conducted in collaboration with companies, universities, and other research centers—focus on the development of new biologically active molecules of varying complexity. This is achieved through Chemical and Molecular Biology techniques, with applications in both therapeutic and diagnostic fields.
In particular, the objective is to identify and characterize novel molecular mechanisms that regulate molecular targeting in systems of different complexity, in order to modulate their biological and genic functions. The unit also studies specific delivery processes for the formulation of new pharmacologically active substances. Research themes revolve around the study of molecular recognition phenomena in complex systems, aiming to develop molecular-based systems capable of modulating biological functions with specific delivery properties. Specifically, research topics include the structural study of protein/protein and protein/oligonucleotide complexes, as well as the design, synthesis, and characterization of peptide systems, peptidomimetics, and modified oligonucleotides for diagnostic and therapeutic applications.
In collaboration with the University, the facility provides access to:
A peptide and PNA synthesis laboratory, equipped with HPLC purification systems;
A spectroscopic characterization laboratory, equipped with Circular Dichroism (CD) and UV/VIS spectrometers;
A Nuclear Magnetic Resonance (NMR) laboratory, featuring 600 MHz and 500 MHz NMR spectrometers equipped with cryoprobes.
