Carrozzini Benedetta

Dr. Benedetta Carrozzini received her M.Sc. degree in Geological Sciences (with honors) at Bari University in 1987 and she got a PhD diploma in Earth Sciences at the same University in 1992. From 1993 to 2000 he was postdoctoral researcher and visiting scientist at the Institute for Crystallographic Methodologies Development (IRMEC) of the National Research Council (CNR), supervisor Prof. C. Giacovazzo. Since February 2001, she has a permanent position as staff researcher at the Institute of Crystallography (CNR) in Bari.

Since 2009 she is the Unit Leader for the CNR research activity devoted to the “Development and application of crystallographic methods for structure determination of molecules, with different nature and complexity, by single crystal (X-rays and electron) diffraction data”.

She is author of crystallographic software packages [SIR suite (vers.1999-2019), Il Milione (vers. 2007), EXPO (vers. 1999)], widely used in scientific labs around the world.

She was involved in several research projects (some currently in progress) and she was Work-TaskLeader for H2020 FET-OPEN AMECRYS Project (2016/2021). In 2016 she was a visiting scientist at the KNU Creative BioResearch Group (Prof. E. di Luccio), in Daegu (South Korea).

In 2008-2011 she was Effective Member of the IUCr Crystallographic Computing Commission, and then Consultant in the following three years.

She is author of over 85 papers in international peer-reviewed journals (Scopus H-index = 21).

She presented several communications at (national and international) meetings and workshops and lectures at international training schools; in many cases she served on their respective scientific and organizing committees.

(detailed list of publications: https://scholar.google.com/citations?user=fXFl3dIAAAAJ&hl=en)

Dr. Carrozzini’s research activity is mainly addressed to:

– development of innovative methodologies aimed at improving the structure determination process of crystal molecules with different chemical composition and structural complexity (i.e. small organic or inorganic compounds up to nucleic acids and proteins),

– implementation of the new theories, algorithms and computing tools in powerful crystallographic software, devoted to the automatic structure solution via single crystal data, using X-ray or electron diffraction patterns.

– Single crystal data analysis for the structure characterization of small compounds and macromolecules.

The main research interests and skills concern: Ab initio phasing approaches (Direct Methods, Patterson Deconvolution techniques), Molecular Replacement, Electron Density Modification (EDM/DEDM) techniques, structure refinement (Fourier analysis), Automated Model Building, X-ray or electron Diffraction, Protein Crystallography.

Università di Perugia – Dipart. di Fisica e Geologia

Università di Bari: Dipart. di Chimica, Scienze del Farmaco, Bioscienze, Biotecnologie e Biofarmaceutica,

CNR: ITM, IPCF