Glioblastoma (GBM) is the most common and lethal primary brain tumour. The prognosis for GBM patients remains poor due to rapid tumour recurrence and resistance to conventional treatments. Small Rho...
Curcumin is recognized for its diverse biological activities, including the ability to induce apoptosis and ferroptosis. Therefore, it represents a promising candidate for the development of new compounds with neuroprotective...
‘Asprinio’ grape is used to produce a white wine from the Campania region, known as ‘Asprinio’ (DOC since 1993). A plethora of approaches was adopted to characterize the organic compounds...
Even though the number of patients suffering from Alzheimer’s Disease (AD) is rapidly growing worldwide, only a few symptomatic treatments have been approved for clinical use, pointing out the urgent...
Background Mature T-cell neoplasms arise from the neoplastic transformation of a single T lymphocyte, and all cells in a neoplastic clone share the same V segment in the beta chain...
Alzheimer's disease (AD) is a neurodegenerative disorder with a high negative impact in terms of cost and social issues. New kinds of noninvasive, reliable, easy-to-use, and cheap biosensors are highly...
The overall crystallographic process involves acquiring experimental data and using crystallographic software to find the structure solution. Unfortunately, while diffracted intensities can be measured, the corresponding phases - needed to...
Angiogenin is a potent angiogenic factor overexpressed in many cancers. In this study, we report the characterization of copper(II) complexes of two peptides from the 40–50 angiogenin domain by means...
Phosphomannomutase-2 (PMM2) deficiency represents the most common congenital disorder of glycosylation (CDG). Currently, little is known about cell metabolic alterations occurring in these patients. Here, we quantified compounds connected to...
Peptide nucleic acids (PNAs) have garnered significant attention due to their enhanced chemical, physical, and binding properties in comparison to natural nucleic acids. This prompted their application in antigene/antisense approach,...
