Glycosylation is the process of combining one or more glucose molecules (or other monosaccharides) with molecules of a different nature (which are therefore glycosylated). In biochemistry, glycosylation is catalyzed by...
A novel double-open-cubane (NNCO)6Co4Cl2 cluster with a Co4O6 core was made available under aqua-ultrasonic open atmosphere conditions for the first time. The ultrasonic clusterization of the (3,5-dimethyl-1H-pyrazol-1-yl)methanol (NNCOH) ligand with...
Nowadays, facile and short synthesis of new antifungal pyrazole-derivatives ligands has attracted increasing attention due to their simplicity and effectiveness. In here, we have prepared a new family of pyrazole...
CNR-IC ha stretto una partnership con BioForDrug per lo sviluppo di sonde a base di Acidi Peptido Nucleici (PNA) per la regolazione di miRNA coinvolti in differenti patologie e per...
CNR-IC ha stretto una partnership con Kedrion per lo sviluppo di un nuovo concentrato di Fattore V plasma derivato come farmaco orfano per la terapia della paraemofilia
Il CNR-IC ha instaurato una partnership con IRBM spa per lo sviluppo di nuove molecole bioattive basate sull'integrazione di tecniche di Biologia Strutturale.
In materials and earth science, but also in chemistry, pharmaceutics and engineering, the quantification of elements and crystal phases in solid samples is often essential for a full characterization of...
Recognition and capture of amyloid beta (Ab) is a challenging task for the early diagnosis of neurodegenerative disorders, such as Alzheimer's disease. Here, we report a novel KLVFF-modified nanomagnet based...
Il laboratorio INSIDEL@b è dedicato all’applicazione di metodi computazionali per caratterizzare e progettare sistemi chimici nell’ambito della ricerca del farmaco e delle tossicologia predittiva. Le attività di ricerca si focalizzano...
Through the IN-SIlico molecular DEsign Laboratory (INSIDEL@b), CNR-IC provides the company NewChem S.p.A. with ligand- and structure-based predictive models for bioactivity and toxicity predictions of drug synthesis intermediates.
