While understanding of periodic recurrent waves of Covid-19 epidemics would aid to combat the pandemics, quantitative analysis of data over a two years period from the outbreak, is lacking. The...
Bando IC_008_2022_CT - Prot. CNR-RM n. 0073798/2022 - Prot. CNR-IC n. 0002449 del 17/10/2022. Provvedimento di graduatoria di merito, con conseguente nomina del vincitore, del bando IC_008_2022_CT per...
Bando IC_007_2022_CT - Prot. CNR-RM n. 0073789/2022 - Prot. CNR-IC n. 0002448 del 17/10/2022 Provvedimento di graduatoria di merito, con conseguente nomina del vincitore, del bando IC_007_2022_CT per il...
Bando IC_006_2022_CT - Prot. CNR-RM n. 0073743/2022 - Prot. CNR-IC n. 0002447 del 17/10/2022 Provvedimento di graduatoria di merito, con conseguente nomina del vincitore, del bando IC_008_2022_CT per il...
Bioconjugates of 2,1,3-benzoxadiazole (benzofurazan) and its derivatives have attracted considerable interest due to their biological activities and applications as fluorescent tags. A high-yield, chemoselective, and mild procedure for theS-alkylation of...
It is beyond doubt that short peptides hold significant promise in bio-medicine, as the most versatile molecules, both structurally and functionally [...].
A recently developed synthetic protocol allowed for the functionalization of the active peptide A9 with a fluorogenic probe, which is useful for studying biomolecular interactions. Essentially, a nucleophilic attack on...
Galectins are soluble ?-D-galactoside-binding proteins whose implication in cancer progression and disease outcome makes them prominent targets for therapeutic intervention. In this frame, the development of small inhibitors that block...
Galectins (Gals) are small cytosolic proteins that bind ?-galactoside residues via their evolutionarily conserved carbohydrate recognition domain. Their dysregulation has been shown to be associated with many diseases. Consequently, targeting...
Drug-induced cardiotoxicity is a common side effect of drugs in clinical use or under postmarket surveillance and is commonly due to off-target interactions with the cardiac human-ether-a-go-go-related (hERG) potassium channel....