The conformational conversion of the cellular prion protein (PrP) into a misfolded, aggregated and infectious scrapie isoform is associated with prion disease pathology and neurodegeneration. Despite the significant number of...
While understanding the time evolution of Covid-19 pandemic is needed to plan economics and tune sanitary policies, a quantitative information of the recurrent epidemic waves is elusive. This work describes...
The crucial role of integrin in pathological processes such as tumor progression and metastasis formation has inspired intense efforts to design novel pharmaceutical agents modulating integrin functions in order to...
We present a combined real and reciprocal space structural and microstructural characterization of CeO nanoparticles (NPs) exhibiting different crystallite sizes; ~3 nm CeO NPs were produced by an inverse micellae...
Complex neurological disorders, including Alzheimer's disease, are one of the major therapeutic areas to which multitarget drug discovery strategies have been applied in the last twenty years. Due to the...
CsPbBrnanoclusters have been synthesized by several groups and mostly employed as single-source precursors for the synthesis of anisotropic perovskite nanostructures or perovskite-based heterostructures. Yet, a detailed characterization of such clusters...
A straightforward approach to new polycyclic heterocycles, 1H-benzo[4,5]imidazo[1,2-c][1,3]oxazin-1-ones, is presented. It is based on the ZnCl-promoted deprotective 6-endo-dig het-erocyclization of N-Boc-2-alkynylbenzimidazoles under mild conditions (CHCl, 40C for 3 h). The...
Perfluorooctanoic acid (PFOA) is a toxic compound that is absorbed and distributed throughout the body by noncovalent binding to serum proteins such as human serum albumin (hSA). Though the interaction...
We present the state-of-art activity of n_TOF Collaboration Working Group dedicated to study how to solve the puzzle about the existence of the so called new particle X17, spotted for...
A new parasitic, mixed-field, neutron-dominated irradiation station has been recently commissioned at the European Laboratory for Particle Physics (CERN). The station is installed within the neutron time-of- flight (n_TOF) facility,...
