Spinal cord injury (SCI) leads to long-term and permanent motor dysfunctions, and nervous system abnormalities. Injury to the spinal cord triggers a signaling cascade that results in activation of the...
The delicate alternation between glycogen synthesis and degradation is governed by the interplay between key regulatory enzymes altering the activity of glycogen synthase and phosphorylase. Among these, the PP1 phosphatase...
The bioavailability of copper (Cu) in human cells may depend on a complex interplay with zinc (Zn) ions. We investigated the ability of the Zn ion to target the human...
DOI: https://doi.org/10.24820/ark.5550190.p011.877 Page 1 ©AUTHOR(S) A Platinum Open Access Journal for Organic Chemistry Paper Free to Authors and Readers DOAJ Seal Arkivoc 2023, part iii, 0-0 to be inserted by...
Innovative computational and graphical tools have been implemented for advancing the crystal structure solution process from powder diffraction data using the EXPO software. These improve the capacity of EXPO to...
In this work it is demonstrated that enantiomerically enriched N-alkyl 2-oxazolinylazetidines undergo exclusive alpha-lithiation, and that the resulting lithiated intermediate is chemically stable but configurationally labile under the given experimental...
An eco-friendly metal-free protocol was developed for the regioselective synthesis of densely functionalized 1,2,3-triazoles through a 1,3-dipolar cycloaddition reaction of alkanone enolates with azides performed in the environmentally responsible choline...
Commentary is given on a paper [Schlesinger et al. (2022). IUCrJ, 9, 406-424.] reporting on ambiguous structure determination from powder data using four different structural models of 4,11-difluoroquinacridone with similar...
Despite recent advances, the crystal structure solution process from powder X-ray diffraction (PXRD) data is still a challenging task. In this article, we present case studies of structure solutions using...
The investigation of poly(3-alkylthiophenes) (P3ATs) has gained great attention in the last decades. Here, we present the synthesis, experimental and theoretical study of the novel regioregular poly(3-adamantylmethylthiophene) (PMAT) and poly(3-adamantylethylthiophene)...
