Institute of Crystallography - CNR
06 90672 676
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Researcher

Moccia Maria

Roma

2003: MSc Organic Chemistry, University of Naples.
2007: PhD in Chemistry under the supervision of Prof. C. Pedone, Department of Biological Science, University of Naples. During PhD worked at Edinburgh University under the supervision of Prof Mark Bradley on “Non enzymatic method for single nucleotide polymorphism analysis”.

2008: Post-doctoral Research Fellows at IBB-CNR on project entitled “Peptide-PNA chimera mimetic of Ni superoxide dismutase (SOD) binding site”.
2009-2011: Awarded Marie Curie fellowship (CEMP) : Development of novel PNA based molecular probes for the detection of c-Myc mRNA.
2011-2012: Senior Post-doctoral Research Fellow in Chemistry at RCSI founded by TIDA and Science Foundation Ireland.
2013-nowdays: Researcher at IC-CNR

Organic synthesis: solution and solid phase synthesis, asymmetric organocatalysis, multicomponent reaction, microwave assisted synthesis.

Oligonucleotide synthesis: manual and automated DNA, DNA analogues, PNA, chimeric DNA/PNA, peptide synthesis.

Purification: organic molecules, peptides, oligonucleotides, PNA, chimeric DNA/PNA.

Chemical characterization of PNA, DNA, chimeric DNA/PNA, peptides and organic molecules (NMR).

Mass Spectrometry: MALDI-TOF ed ESI-MS

Spectroscopic techniques: Fluorescence, IR, UV, CD.

Prof. Mauro F. A. Adamo
Professor of Organic and Medicinal Chemistry (RCSI); Dublin, Ireland.

Brian Kelly Ceo

KelAda Pharmachem

Science Centre south, Belfield, Dublin 4, Ireland.

Prof. Fabiana Arduini,

Department of Chemical Science and Technologies (Laboratory of Analytical Chemistry),

University of Rome Tor Vergata, Roma

Prof. Daniela Marasco

Professor  of general and inorganic chemistry

University of Naples Federico II

Dott. Marilisa Leone

CNR-Institute of Biostructures and Bioimages

 

Innovative devices for Shaping the Risk of Diabetes
Biosensori point-of-care basati su PNA per la diagnosi e il monitoraggio terapeutico non invasivo del tumore al colon retto
Automatic Synthesis of Peptides/PNA and Mass Spectrometry
Synthesis, development and optimization of chemo-enzymatic, organ catalytic and enantioselective procedures for the preparation of chiral molecules) and active pharmaceutical compounds (APIs).
Design, synthesis and development of peptide nucleic acid (PNA) based analogues for miRNAs targeting in therapeutic and diagnostic fields
Design, synthesis and development of peptide-based molecules and peptido mimetics for therapeutic and diagnostic
Molecular Targeting and Delivery
Moccia Maria
Curriculum
Veronica Caratelli, Maria Moccia, Francesca R Paggioro, Luca Fiore, Concetta Avitabile, Michele Saviano, Anna Lisa Imbriani, Principia Dardano, Luca De Stefano, Danila Moscone, Nicola A Colabufo, Imane Ghafir El Idrissi, Francesco Russo, Giuseppe Riezzo, Gianluigi Giannelli, Fabiana Arduini. (2022)
Liquid Biopsy beyond Cancer: A miRNA Detection in Serum with Electrochemical Chip for Non-Invasive Coeliac Disease Diagnosis
Bencivenni G.; Salazar Illera D.; Moccia M.; Houk K.N.; Izzo J.A.; Novacek J.; Grieco P.; Vetticatt M.J.; Waser M.; Adamo M.F.A. (2021)
Study of Ground State Interactions of Enantiopure Chiral Quaternary Ammonium Salts and Amides, Nitroalkanes, Nitroalkenes, Esters, Heterocycles, Ketones and Fluoroamides
Caratelli V.; Fillo S.; D’Amore N.; Rossetto O.; Pirazzini M.; Moccia M.; Avitabile C.; Moscone D.; Lista F.; Arduini F. (2021)
Paper-based electrochemical peptide sensor for on-site detection of botulinum neurotoxin serotype A and C
Zito G.; Sanita G.; Guilcapi Alulema B.; Lara Yepez S.N.; Lanzio V.; Riminucci F.; Cabrini S.; Moccia M.; Avitabile C.; Lamberti A.; Mocella V.; Rendina I.; Romano S. (2021)
Label-free DNA biosensing by topological light confinement