Energy management in cells is a tightly regulated process critical for maintaining homeostasis, supporting survival, and responding to environmental changes at both the cellular and systemic levels. Central to this...
Recently, there has been a surge of interest in developing new types of photothermal materials driven by the ongoing demand for efficient energy conversion, environmental concerns, and the need for...
In recent years, investigation of new or combined therapeutic modalities for cancer treatment lead to relevant scientific advances. Among these innovative therapeutic modalities photothermal therapy (PTT) attracts attention as an...
The urgent need for antibiotic alternatives has driven the search for antimicrobial peptides (AMPs) from many different sources, yet parasite-derived AMPs remain underexplored. In this study, three novel potential AMP...
Nowadays, wound management represents a major medical issue for patients with chronic and autoimmune disease due to several complications associated with pro-inflammatory milieu and bacterial accumulation [1]. Recent advances for...
: Vascular endothelial growth factor (VEGF) is best known for its role in angiogenesis, but emerging evidence suggests neurotrophic and neuroprotective functions most likely connected to energy homeostasis pathways. Using...
Decreased proteasome activity is a hallmark of brain and retinal neurodegenerative diseases (Alzheimer’s, Parkinson’s diseases, glaucoma) boosting the search for molecules acting as proteasome activators. Based on the hypothesis of...
Astaxanthin (AXT), a carotenoid primarily derived from marine organisms such as shrimp, krill and the microalga Haematococcus pluvialis, has gained significant attention for its potent antioxidant, anti-inflammatory and anti-proliferative properties....
The proteasome is a central component of the cellular machinery responsible for degrading misfolded or damaged proteins, thereby maintaining protein homeostasis. Dysregulation of proteasome activity has been implicated in various...
HK1 and HK2 Beyond Glycolysis: Mitochondrial Interactions and Dual Roles in Metabolism and Cell Fate
aging, apoptosis, cancer, HK-VDAC, metabolism, mitochondria, Warburg effect
