The hard and soft acids and bases (HSAB) principle provides a foundational framework for predicting metal-ligand affinity. In biological systems, sulfur and selenium often display antagonistic behavior in binding metal...
Emerging evidence has demonstrated that cannabinoid receptor 2 (CB2) is involved in a number of diseases, such as neurodegenerative disorders and various types of cancer, making it an attractive pharmacological...
Developing user-friendly, high-performance sensing devices for nucleic acid detection is crucial for diagnostics, drug development, and personalized therapies. Nanotechnologies offer innovative solutions to meet this need, utilizing the organization and...
Thioredoxin reductase 1 (TrxR1), a selenoprotein enzyme crucial for redox homeostasis in mammals, has emerged as a promising target for anticancer therapy. In this study, we present a non-covalent TrxR1...
A new experimental area, the NEAR station, has recently been built at the CERN n_TOF facility, at a short distance from the spallation target (3 m). The new area, characterized...
Lysozyme-sensitive plasmonic hydrogel nanocomposite for colorimetric dry-eye inflammation biosensing
Detection of lysozyme levels in ocular fluids is considered crucial for diagnosing and monitoring various health and eye conditions, including dry-eye syndrome. Hydrogel-based nanocomposites have been demonstrated to be one...
Lubeluzole is a neuroprotective agent displaying antimyotonic activity. Lubeluzole clinical development as an antiischemic drug was discontinued due to a lack of efficacy in human trials and possible cardiac toxicity....
The controlled assembly of nanocrystals (NCs) in 3D systems is an intriguing strategy to engineer innovative materials with advanced functionalities. Herein, undoped and manganese-doped cesium lead mixed halide perovskite NCs...
The sulfate-bearing sublimate samples from Somma-Vesuvius, collected in the Royal Mineralogical Museum of Naples University Federico II (Italy), record historical exhalative events of this volcano, whose products are no longer...
Metasurfaces are the 2D counterparts of metamaterials, and their development is accelerating rapidly in the past years. This progress enables the creation of devices capable of uniquely manipulating light, with...
