The urgent need for antibiotic alternatives has driven the search for antimicrobial peptides (AMPs) from many different sources, yet parasite-derived AMPs remain underexplored. In this study, three novel potential AMP...
Nowadays, wound management represents a major medical issue for patients with chronic and autoimmune disease due to several complications associated with pro-inflammatory milieu and bacterial accumulation [1]. Recent advances for...
: Vascular endothelial growth factor (VEGF) is best known for its role in angiogenesis, but emerging evidence suggests neurotrophic and neuroprotective functions most likely connected to energy homeostasis pathways. Using...
Decreased proteasome activity is a hallmark of brain and retinal neurodegenerative diseases (Alzheimer’s, Parkinson’s diseases, glaucoma) boosting the search for molecules acting as proteasome activators. Based on the hypothesis of...
Astaxanthin (AXT), a carotenoid primarily derived from marine organisms such as shrimp, krill and the microalga Haematococcus pluvialis, has gained significant attention for its potent antioxidant, anti-inflammatory and anti-proliferative properties....
The proteasome is a central component of the cellular machinery responsible for degrading misfolded or damaged proteins, thereby maintaining protein homeostasis. Dysregulation of proteasome activity has been implicated in various...
HK1 and HK2 Beyond Glycolysis: Mitochondrial Interactions and Dual Roles in Metabolism and Cell Fate
aging, apoptosis, cancer, HK-VDAC, metabolism, mitochondria, Warburg effect
: Macroporous cryogels (Cry) represent a versatile class of scaffolds with broad applicability in biomedical fields, including biomolecular immobilization, diagnostic sensing, and tissue engineering. More recently, their application in neuroscience...
: SUMOylation is a post-translational modification involving the addition of SUMO isoforms to target proteins and plays a role in various biological processes, including neurodegenerative diseases and ocular pathologies. This...
Alzheimer’s disease (AD) is the most common neurodegenerative disorder associated with cognitive decline and loss of memory. It is postulated that the generation of reactive oxygen species (ROS) in Fenton-like...
