We examined the reaction of hydroxyl radicals (HOo) and sulfate radical anions (SO4o-), which is generated by ionizing radiation in aqueous solutions under anoxic conditions, with an alternating GC doubled-stranded...
Microcalcifications, small deposits of calcium-containing minerals that form in breast tissue, are often, but not always, a warning sign of breast cancer. The relationship between microcalcifications and cancer has not...
The development of small molecules that selectively target the cannabinoid receptor subtype 2 (CB2R) is emerging as an intriguing therapeutic strategy to treat neurodegeneration, as well as to contrast the...
The development of effective drugs to treat coronavirus infections remains a significant challenge for the scientific community. Recent evidence reports on the sigma-1 receptor (S1R) as a key druggable host...
GENERA: A Combined Genetic/Deep-Learning Algorithm for Multiobjective Target-Oriented De Novo Design
This study introduces a new de novo design algorithm called GENERA that combines the capabilities of a deep-learning algorithm for automated drug-like analogue design, called DeLA-Drug, with a genetic algorithm...
Per i soli dipendenti a Tempo Indeterminato e Determinato Si chiede di comunicare compilando il modulo allegato le eventuali ore fruite per la formazione professionale nel mese precedente.
Il 26 settembre 2023, nell’ambito della “European Biotech Week”, si è tenuto a Catania l’evento “Porte aperte al CNR” che ha coinvolto, in maniera congiunta, l’attività di divulgazione-formazione dell’Istituto di...
Flexible perovskite solar cells are lightweight, bendable, and applicable to curved surfaces. Polyethylene terephthalate (PET) has become the substrate of choice compared to other plastic substrates like polyethylene naphthalate. PET...
Workshop congiunto tra ricercatori dell'IC e della Ivodent Academy (Tirana, Albania), con focus su materiali e metodologie sviluppate da entrambe le parti per applicazioni biomediche Referenti IC: Francesco Capitelli
HMGA proteins are intrinsically disordered (ID) chromatin architectural factors characterized by three DNA binding domains (AT-hooks) that allow them to bind into the DNA minor groove of AT-rich stretches. HMGA...
