Istituto di Cristallografia - CNR
Ricercatore

Mangiatordi Giuseppe Felice

Bari

Giuseppe Felice Mangiatordi obtained his M.Sc. degree in Chemistry and Pharmaceutical Technology cum laude at the University of Bari in 2008 and a PhD in theoretical chemistry at the École Nationale Supérieure de Chimie de Paris (ENSCP – Paris) in 2012. From 2013 to 2017 he was postdoctoral researcher at the University of Bari (Dipartimento di Farmacia – Scienze del Farmaco). Since December 2018 he has a permanent position as researcher of the National Research Council (CNR) where he is head of the in-silico design laboratory (INSIDEL@b). He has major expertise in structure- and ligand based drug design, Molecular Dynamics (MD) simulations and predictive toxicology.  His is author of 81 papers in international peer-reviewed journals and 12 lectures at international meetings.

Molecular Docking Simulations – Molecular Dynamics – QSAR – De-novo design – DFT

Macchia, Eleonora; De Caro, Liberato; Torricelli, Fabrizio; Franco, Cinzia Di; Mangiatordi, Giuseppe Felice; Scamarcio, Gaetano; Torsi, Luisa (2022)
Why a Diffusing Single-Molecule can be Detected in Few Minutes by a Large Capturing Bioelectronic Interface
Spinetti E.; Delre P.; Saviano M.; Siliqi D.; Lattanzi G.; Mangiatordi G.F. (2022)
A Comparative Molecular Dynamics Study of Selected Point Mutations in the Shwachman-Bodian-Diamond Syndrome Protein SBDS
Creanza, Teresa Maria; Lamanna, Giuseppe; Delre, Pietro; Contino, Marialessandra; Corriero, Nicola; Saviano, Michele; Mangiatordi, Giuseppe Felice; Ancona, Nicola (2022)
DeLA-Drug: A Deep Learning Algorithm for Automated Design of Druglike Analogues
Belviso B.D.; Mangiatordi G.F.; Alberga D.; Mangini V.; Carrozzini B.; Caliandro R. (2022)
Structural Characterization of the Full-Length Anti-CD20 Antibody Rituximab
Delre, Pietro; Lavado, Giovanna J.; Lamanna, Giuseppe; Saviano, Michele; Roncaglioni, Alessandra; Benfenati, Emilio; Mangiatordi, Giuseppe Felice; Gadaleta, Domenico (2022)
Ligand-based prediction of hERG-mediated cardiotoxicity based on the integration of different machine learning techniques
Mansouri, Kamel; Karmaus, Agnes L.; Fitzpatrick, Jeremy; Patlewicz, Grace; Pradeep, Prachi; Alberga, Domenico; Alepee, Nathalie; Allen, Timothy E.H.; Allen, Dave; Alves, Vinicius M.; Andrade, Carolina H.; Auernhammer, Tyler R.; Ballabio, Davide; Bell, Shannon; Benfenati, Emilio; Bhattacharya, Sudin; Bastos, Joyce V.; Boyd, Stephen; Brown, J. B.; Capuzzi, Stephen J.; Chushak, Yaroslav; Ciallella, Heather; Clark, Alex M.; Consonni, Viviana; Daga, Pankaj R.; Ekins, Sean; Farag, Sherif; Fedorov, Maxim; Fourches, Denis; Gadaleta, Domenico; Gao, Feng; Gearhart, Jeffery M.; Goh, Garett; Goodman, Jonathan M.; Grisoni, Francesca; Grulke, Christopher M.; Hartung, Thomas; Hirn, Matthew; Karpov, Pavel; Korotcov, Alexandru; Lavado, Giovanna J.; Lawless, Michael; Li, Xinhao; Luechtefeld, Thomas; Lunghini, Filippo; Mangiatordi, Giuseppe F.; Marcou, Gilles; Marsh, Dan; Martin, Todd; Mauri, Andrea; Muratov, Eugene N.; Myatt, Glenn J.; Nguyen, Dac Trung; Nicolotti, Orazio; Note, Reine; Pande, Paritosh; Parks, Amanda K.; Peryea, Tyler; Polash, Ahsan H.; Rallo, Robert; Roncaglioni, Alessandra; Rowlands, Craig; Ruiz, Patricia; Russo, Daniel P.; Sayed, Ahmed; Sayre, Risa; Sheils, Timothy; Siegel, Charles; Silva, Arthur C.; Simeonov, Anton; Sosnin, Sergey; Southall, Noel; Strickland, Judy; Tang, Yun; Teppen, Brian; Tetko, Igor V.; Thomas, Dennis; Tkachenko, Valery; Todeschini, Roberto; Toma, Cosimo; Tripodi, Ignacio; Trisciuzzi, Daniela; Tropsha, Alexander; Varnek, Alexandre; Vukovic, Kristijan; Wang, Zhongyu; Wang, Liguo; Waters, Katrina M.; Wedlake, Andrew J.; Wijeyesakere, Sanjeeva J.; Wilson, Dan; Xiao, Zijun; Yang, Hongbin; Zahoranszky-Kohalmi, Gergely; Zakharov, Alexey V.; Zhang, Fagen F.; Zhang, Zhen; Zhao, Tongan; Zhu, Hao; Zorn, Kimberley M. (2021)
CATMoS: Collaborative acute toxicity modeling suite
Sang Hee Lee, Nunzio Denora, Valentino Laquintana, Giuseppe Felice Mangiatordi, Angela Lopedota, Antonio Lopalco, Annalisa Cutrignelli, Massimo Franco, Pietro Delre, In Ho Song, Hye Won Kim, Su Bin Kim, Hyun Soo Park, Kyungmin Kim, Seok-Yong Lee, Hyewon Youn, Byung Chul Lee & Sang Eun Kim (2021)
Radiosynthesis and characterization of [18F]BS224: a next-generation TSPO PET ligand insensitive to the rs6971 polymorphism
Prencipe, Filippo; Zanfardino, Anna; Di Napoli, Michela; Rossi, Filomena; D’errico, Stefano; Piccialli, Gennaro; Mangiatordi, Giuseppe Felice; Saviano, Michele; Ronga, Luisa; Varcamonti, Mario; Tesauro, Diego (2021)
Silver (I) n-heterocyclic carbene complexes: A winning and broad spectrum of antimicrobial properties
Di Gaetano S.; Capasso D.; Delre P.; Pirone L.; Saviano M.; Pedone E.; Mangiatordi G.F. (2021)
More is always better than one: The n-terminal domain of the spike protein as another emerging target for hampering the sars-cov-2 attachment to host cells
Creanza T.M.; Delre P.; Ancona N.; Lentini G.; Saviano M.; Mangiatordi G.F. (2021)
Structure-Based Prediction of hERG-Related Cardiotoxicity: A Benchmark Study
Sarcina, Lucia; Mangiatordi, Giuseppe Felice; Torricelli, Fabrizio; Bollella, Paolo; Gounani, Zahra; Österbacka, Ronald; Macchia, Eleonora; Torsi, Luisa (2021)
Surface plasmon resonance assay for label-free and selective detection of hiv-1 p24 protein
Emanuele M. Gargano, Abdelrahman Mohamed, Ahmed S. Abdelsamie, Giuseppe F. Mangiatordi, Hanna Drzewiecka, Pawe? P. Jagodzi?ski, Arcangela Mazzini, Chris J. van Koppen, Matthias W. Laschke, Orazio Nicolotti, Angelo Carotti, Sandrine Marchais-Oberwinkler, Rolf W. Hartmann, and Martin Frotscher (2021)
17?-Hydroxysteroid Dehydrogenase Type 1 Inhibition: A Potential Treatment Option for Non-Small Cell Lung Cancer
Gnocchi, Davide; Cavalluzzi, Maria M.; Mangiatordi, Giuseppe F.; Rizzi, Rosanna; Tortorella, Cosimo; Spennacchio, Mauro; Lentini, Giovanni; Altomare, Angela; Sabbà, Carlo; Mazzocca, Antonio (2021)
Xanthenylacetic Acid Derivatives Effectively Target Lysophosphatidic Acid Receptor 6 to Inhibit Hepatocellular Carcinoma Cell Growth