Thin and/or polycrystalline films are studied by X-ray Diffraction and/or Reflectivity, by using a Bruker D8 Discover diffractometer in parallel beam configuration. Reflection or transmission geometry can be used to...
The diffractometer is devoted to research and/or service activities executing measures aimed at the following purposes: 1) data collection; 2) qualitative analysis using QUALX2.0 software, developed by IC researchers; 3)...
Laboratory is devoted mainly to the preparation of biological samples before performing measurements through x-ray, such as diffraction from crystals (MX) or Small/ Wide Angle Scattering (SAXS, WAXS), at the...
XRD1 beamline is a multipurpose X ray diffraction beamline. The beamline source is a multipole wiggler producing an intense beam in the 4-21 keV energy range where a tunable double...
The peptide synthesis group of IC-CNR in Trieste cooperates with the peptide synthesis workstation of Department of Life Sciences (DSC) of University of Trieste, to achieve the synthesis and characterization...
The protein expression and purification laboratory provides highly pure protein samples suitable for structural studies. It employs traditional and Restriction free cloning techniques to construct expression plasmids, using a wide...
The Biophysical Characterization Laboratory houses a range of equipment for the analysis of the biophysical properties of proteins as well as intermolecular interactions. Techniques available include: • UV-visible spectrophotometry; •...
Through the IN-SIlico molecular DEsign Laboratory (INSIDEL@b), CNR-IC provides the company NewChem S.p.A. with ligand- and structure-based predictive models for bioactivity and toxicity predictions of drug synthesis intermediates.
The IN-SIlico molecular DEsign Laboratory (INSIDEL@b) of CNR-IC has established a partnership with Istituto di Ricerche Farmacologiche Mario Negri for the development of ligand-based models based on the integration of...
INSIDEL@b is devoted to the application of computational methods to understand, characterize and design chemical systems in the context of drug discovery and predictive toxicology. Research activities focus on: i)...