Bari
Direttore di Istituto: Cinzia Giannini
Contacts
segreteria@ic.cnr.it
+39 0805929142/41
Address
Bari
VIA GIOVANNI AMENDOLA 122/O 70126 BARI (IT)
STAFF
Laboratories
BioSAXSBioSAXS is a technique used for structural studies of proteins in their native state. BioSAXS helps identify structural states and changes of biological macromolecules and relate these changes to their functions. In fact, many diseases are related to the misfolding of biological macromolecules. Structure changes can occur as a function of time, pH, ionic strength,… |
INSIDEL@b (In-silico molecular design laboratory)INSIDEL@b is devoted to the application of computational methods to understand, characterize and design chemical systems in the context of drug discovery and predictive toxicology. Research activities focus on: i) structure-based and ligand-based drug design; ii) development of algorithms for bioactivity and toxicity prediction; iii) application of molecular dynamics simulations on complex biological systems; iv)… |
Bio-crystallography preparation laboratoryLaboratory is devoted mainly to the preparation of biological samples before performing measurements through x-ray, such as diffraction from crystals (MX) or Small/ Wide Angle Scattering (SAXS, WAXS), at the instrumentations of our institute and / or synchrotron facilities. Preparation consists of purification and, if necessary, subsequent crystallization. In addition, the laboratory is used as… |
X-ray diffractometer RINT2500 RIGAKUThe diffractometer is devoted to research and/or service activities executing measures aimed at the following purposes: 1) data collection; 2) qualitative analysis using QUALX2.0 software, developed by IC researchers; 3) structural characterization by applying the EXPO software developed by IC researchers. |
X-ray Diffraction & ReflectivityThin and/or polycrystalline films are studied by X-ray Diffraction and/or Reflectivity, by using a Bruker D8 Discover diffractometer in parallel beam configuration. Reflection or transmission geometry can be used to investigate the crystal structure of flat samples or powders inserted in capillaries, respectively. In the last case, the capillary is mounted on a rotation stage… |
X-ray MicroImaging Laboratory (XMI-L@B)This Imaging X-ray diffraction facility allows for molecular and atomic scale analysis of fabrics, natural or engineered biotissues, thin films, nanocomposites, nanostructured surfaces, nanocrystal assemblies, polymers, colloidal solutions. Data are collected with scattering contrast, in the small and wide angle ranges, in transmission (SAXS/WAXS) or reflection geometry (GISAXS/GIWAXS), as well as with absorption contrast. SAXS… |
Single Crystal X-Ray Diffractometry LaboratoryThe Bruker-Nonius KappaCCD single-crystal X-ray diffractometer provides diffraction data that allow to carry out the structural characterization of crystalline materials with different chemical composition and complexity (small and medium molecules, up to about 150 non-H atoms in the asymmetric unit): synthetic compounds (organic, inorganic and metalorganic compounds, including, for example, new materials of technological and… |
